ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4) (N-Term) Peptide
ABCB4
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits ABCB4
- ABCB4 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4))
- Protein Region
- N-Term
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-ABCB4 antibody (Catalog #: ARP41741_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- ABCB4 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4))
- Synonymes
- ABC21 Peptide, GBD1 Peptide, ICP3 Peptide, MDR2 Peptide, MDR2/3 Peptide, MDR3 Peptide, PFIC-3 Peptide, PGY3 Peptide, zgc:172149 Peptide, Mdr2 Peptide, Pgy-2 Peptide, Pgy2 Peptide, mdr-2 Peptide, Pgy3 Peptide, ABCB4a Peptide, DEFB1 Peptide, PGP2 Peptide, PGY2 Peptide, PGP3 Peptide, ABCB4 Peptide, RUNDC3B Peptide, ATP binding cassette subfamily B member 4 Peptide, ATP-binding cassette, sub-family B (MDR/TAP), member 4 Peptide, beta-defensin 1-like Peptide, ATP-binding cassette, sub-family B (MDR/TAP), member 1B Peptide, RUN domain-containing protein 3B Peptide, ABCB4 Peptide, abcb4 Peptide, Abcb4 Peptide, LOC100861170 Peptide, Abcb1b Peptide, LOC101122517 Peptide
- Sujet
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ABCB4, a membrane-associated protein, is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. ABCB4 is a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined, however, it may involve transport of phospholipids from liver hepatocytes into bile.The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined, however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function.
Alias Symbols: ABC21, GBD1, MDR2, MDR2/3, MDR3, PFIC-3, PGY3
Protein Interaction Partner: HAX1
Protein Size: 1279 - Poids moléculaire
- 141 kDa
- ID gène
- 5244
- NCBI Accession
- NM_000443, NP_000434
- UniProt
- A4D1D4
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