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Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (C-Term) Peptide

FGF8 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN976837
  • Antigène Tous les produits FGF8
    FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))
    Protein Region
    C-Term
    Origine
    Humain
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Séquence
    EGWYMAFTRK GRPRKGSKTR QHQREVHFMK RLPRGHHTTE QSLRFEFLNY
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-FGF8 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))
    Synonymes
    Aigf Peptide, Fgf-8 Peptide, AIGF Peptide, FGF-8 Peptide, HBGF-8 Peptide, HH6 Peptide, KAL6 Peptide, fibroblast growth factor 8 Peptide, Fgf8 Peptide, FGF8 Peptide
    Sujet
    The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants.

    Alias Symbols: AIGF, HBGF-8, KAL6, MGC149376, FGF-8

    Protein Interaction Partner: AR,FGFR1,FGFR2,FGFR3,FGFR4,FGFR3

    Protein Size: 215
    Poids moléculaire
    22 kDa
    ID gène
    2253
    NCBI Accession
    NM_006119, NP_006110
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