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KH-Type Splicing Regulatory Protein (KHSRP) (Middle Region) Peptide

KHSRP Reactivité: Humain Hôte: Synthetic WB, BP, IHC
N° du produit ABIN978887
  • Antigène Tous les produits KHSRP
    KHSRP (KH-Type Splicing Regulatory Protein (KHSRP))
    Protein Region
    Middle Region
    Origine
    Humain
    Source
    • 4
    Synthetic
    Application
    Western Blotting (WB), Blocking Peptide (BP), Immunohistochemistry (IHC)
    Séquence
    WEEYYKKQAQ VATGGGPGAP PGSQPDYSAA WAEYYRQQAA YYGQTPGPGG
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-KHSRP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    KHSRP (KH-Type Splicing Regulatory Protein (KHSRP))
    Synonymes
    FBP2 Peptide, FUBP2 Peptide, KSRP Peptide, 6330409F21Rik Peptide, Fbp2 Peptide, Fubp2 Peptide, Ksrp Peptide, Marta1 Peptide, KHSRP Peptide, VgRBP71 Peptide, fbp2 Peptide, ksrp Peptide, fubp2 Peptide, fc94c12 Peptide, wu:fb25b12 Peptide, wu:fc10e10 Peptide, wu:fc94c12 Peptide, zgc:163038 Peptide, khsrp-b Peptide, KH-type splicing regulatory protein Peptide, KH-type splicing regulatory protein L homeolog Peptide, KH-type splicing regulatory protein S homeolog Peptide, KHSRP Peptide, Khsrp Peptide, khsrp.L Peptide, khsrp Peptide, khsrp.S Peptide
    Sujet
    KHSRP binds to the dendritic targeting element and may play a role in mRNA trafficking. It is part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. KHSRP mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. It may interact with single-stranded DNA from the far-upstream element (FUSE).It is also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.

    Alias Symbols: FBP2, FUBP2, KSRP, MGC99676

    Protein Size: 711
    Poids moléculaire
    73 kDa
    ID gène
    8570
    NCBI Accession
    NM_003685, NP_003676
    UniProt
    Q92945
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