Mediator Complex Subunit 6 (MED6) (Middle Region) Peptide
MED6
Reactivité: Humain
Hôte: Synthetic
BP, WB, ChIP
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- Antigène Tous les produits MED6
- MED6 (Mediator Complex Subunit 6 (MED6))
- Protein Region
- Middle Region
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-MED6 antibody (Catalog #: ARP34219_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- MED6 (Mediator Complex Subunit 6 (MED6))
- Synonymes
- NY-REN-28 Peptide, wu:fa14c11 Peptide, zgc:86933 Peptide, 1500012F11Rik Peptide, AU019660 Peptide, AV213303 Peptide, RNA polymerase transcriptional regulation mediator-like protein Peptide, mediator complex subunit 6 Peptide, hypothetical protein Peptide, MED6 Peptide, Med6 Peptide, med6 Peptide, CAALFM_C306170CA Peptide
- Sujet
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MED6 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. And mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Alias Symbols: NY-REN-28
Protein Interaction Partner: PARP1,RARA,MED25,MED8,MED9,PARP1,RARA,SMAD1,SMAD2,CDK8,ESR1,ESR2,MED1,MED10,MED14,MED15,MED19,MED21,MED25,MED26,MED28,MED29,MED30,MED9,THRA,VDR
Protein Size: 246 - Poids moléculaire
- 28 kDa
- ID gène
- 10001
- NCBI Accession
- NM_005466, NP_005457
- UniProt
- O75586
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