This is a synthetic peptide designed for use in combination with anti-Nfkbiz Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Conseil sur la manipulation
Avoid repeated freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Antigène
NFKBIZ
(Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, zeta (NFKBIZ))
Synonymes
RGD1310834 Peptide, NFKBIZ Peptide, MAIL Peptide, AA408868 Peptide, INAP Peptide, Mail Peptide, IKBZ Peptide, NFKB inhibitor zeta Peptide, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta Peptide, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta Peptide, Nfkbiz Peptide, NFKBIZ Peptide, nfkbiz Peptide
Sujet
Nfkbiz is involved in regulation of NF-kappa-B transcription factor complexes. It inhibits NF-kappa-B activity without affecting its nuclear translocation upon stimulation. It inhibits DNA-binding of RELA and NFKB1/p50, and of the NF-kappa-B p65-p50 heterodimer and the NF-kappa-B p50-p50 homodimer. It seems also to activate NF-kappa-B-mediated transcription. In vitro, upon association with NFKB1/p50, Nfkbiz has transcriptional activation activity and, together with NFKB1/p50 and RELA, Nfkbiz is recruited to LCN2 promoters.
Alias Symbols: AA408868, INAP, Mail
Protein Interaction Partner: Il6,Nfkb1,Ehf,Elf5,Ikbkg,Nfkb1,Nfkb2