Nucleolar Protein 6 (NOL6) (N-Term) Peptide
NOL6
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits Nucleolar Protein 6 (NOL6)
- Nucleolar Protein 6 (NOL6)
- Protein Region
- N-Term
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-NOL6 antibody (Catalog #: ARP40994_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- Nucleolar Protein 6 (NOL6)
- Synonymes
- NRAP Peptide, UTP22 Peptide, bA311H10.1 Peptide, nrap Peptide, utp22 Peptide, AA410091 Peptide, Nrap Peptide, nucleolar protein 6 Peptide, nucleolar protein 6 L homeolog Peptide, nucleolar protein family 6 (RNA-associated) Peptide, NOL6 Peptide, Nol6 Peptide, nol6.L Peptide
- Sujet
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NOL6 is a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. The nucleolus is a dense subnuclear membraneless organelle that assembles around clusters of rRNA genes and functions in ribosome biogenesis. This gene encodes a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. Alternative splicing has been observed at this locus and two splice variants encoding distinct isoforms have been identified.
Alias Symbols: FLJ21959, MGC14896, MGC14921, MGC20838, NRAP, UTP22, bA311H10.1
Protein Interaction Partner: G3BP1
Protein Size: 1146 - Poids moléculaire
- 127 kDa
- ID gène
- 65083
- NCBI Accession
- NM_022917, NP_075068
- UniProt
- Q9H6R4
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