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SMAD, Mothers Against DPP Homolog 5 (SMAD5) Peptide

SMAD5 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN984103
  • Antigène Tous les produits SMAD5
    SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))
    Origine
    Humain
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-SMAD5 antibody (Catalog #: ARP32006_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))
    Synonymes
    DWFC Peptide, JV5-1 Peptide, MADH5 Peptide, Madh5 Peptide, SBN Peptide, fb67b04 Peptide, mad Peptide, madh5 Peptide, sb:cb400 Peptide, smd5 Peptide, wu:fb67b04 Peptide, SMAD5 Peptide, DKFZp468M0619 Peptide, 1110051M15Rik Peptide, AI451355 Peptide, Dwf-C Peptide, MusMLP Peptide, SMAD family member 5 Peptide, SMAD5 Peptide, Smad5 Peptide, smad5 Peptide
    Sujet
    SMAD5 undergoes copy number gain and increased expression, rather than loss of expression, and therefore does not act as a tumor-suppressor gene in hepatocellular carcinoma. Up-regulated Smad5 mediates apoptosis of gastric epithelial cells induced by Helicobacter pylori infection.

    Alias Symbols: DWFC, JV5-1, MADH5

    Protein Interaction Partner: ACVR1,BCAT1,BMP6,CXXC5,FLNA,GDF6,HBG2,HOXA13,HOXD13,MBD1,MEN1,MTMR10,PNKP,PPIL4,PSMD11,PTPN12,RBM4,RYR2,SF3B1,SFPQ,SMAD1,SMAD4,SMURF2,SNRNP70,SNRPA,SOX5,SOX7,SUV39H1,SUV39H2,TOB1,U2AF2,VPS24,WWP1,ZEB2,ZNF8,ACVR1,PLEKHO1,RUNX1,RUNX2,RUNX3,SMAD4,SMURF1,TOB1,Zfp128

    Protein Size: 465
    Poids moléculaire
    51 kDa
    ID gène
    4090
    NCBI Accession
    NM_005903, NP_005894
    UniProt
    Q99717
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