Wingless-Type MMTV Integration Site Family, Member 6 (WNT6) (Middle Region) Peptide
WNT6
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits WNT6
- WNT6 (Wingless-Type MMTV Integration Site Family, Member 6 (WNT6))
- Protein Region
- Middle Region
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-WNT6 antibody (Catalog #: ARP46733_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- WNT6 (Wingless-Type MMTV Integration Site Family, Member 6 (WNT6))
- Synonymes
- WNT6 Peptide, si:dkey-31m21.2 Peptide, Wnt6 Peptide, AA409270 Peptide, Wnt-6 Peptide, Xwnt-6 Peptide, wnt-6 Peptide, wnt6-A Peptide, xWnt6 Peptide, Wnt family member 6 Peptide, wingless-type MMTV integration site family, member 6b Peptide, wingless-type MMTV integration site family, member 6 Peptide, Wnt family member 6 S homeolog Peptide, WNT6 Peptide, Wnt6 Peptide, wnt6b Peptide, wnt6.S Peptide
- Sujet
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The WNT family consists of several secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT6 is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The WNT6 protein overexpression may play key roles in carcinogenesis. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97 % identical to the mouse Wnt6 protein at the amino acid level.
Alias Symbols: -
Protein Interaction Partner: PORCN
Protein Size: 365 - Poids moléculaire
- 37 kDa
- ID gène
- 7475
- NCBI Accession
- NM_006522, NP_006513
- UniProt
- Q9Y6F9
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