This is a synthetic peptide designed for use in combination with anti-TTP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
TTP is a mRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE)-containing mRNAs. It acts by specifically binding ARE-containing mRNAs and promoting their degradation. It recruits deadenylase CNOT7 (and probably the CCR4-NOT complex) via association with CNOT1. Plays a key role in the post- transcriptional regulation of tumor necrosis factor (TNF). And it plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF).