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PKC theta Produits

(Protein Kinase C, theta (PRKCQ))

Catégories

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. [provided by RefSeq, Jul 2008].

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Catégories PKC theta en vedette

PKC theta Anticorps

High quality antibodies with extensive validation data.

PKC theta Kits ELISA

Reliable ELISA kits for a wide range of species.

PKC theta Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PKC theta recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (5)
N° du produit ABIN6256401
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, ELISA, IF
Validations
  • (4)
N° du produit ABIN7138678
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, IP, IHC (f)
Validations
  • (5)
  • (4)
N° du produit ABIN967739
Quantité 150 μg
Fiche technique Fiche technique

PKC theta recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6962224
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN1116786
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN1116787
Quantité 96 tests
Fiche technique Fiche technique

PKC theta recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Insect cells (Sf9)
Validations
  • (2)
N° du produit ABIN5570620
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1316274
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3134783
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits PKC theta

van Rees, Lago, Cox, Tomasik, Rustogi, Weigelt, Ozcan, Cooper, Drexhage, Leweke, Bahn: "Evidence of microglial activation following exposure to serum from first-onset drug-naïve schizophrenia patients." dans: Brain, behavior, and immunity, Vol. 67, pp. 364-373, (2018) (PubMed).

Marino, Hinds, Potter, Ondrus, Onion, Dowling, McLoughlin, Sanchez, Hill: "Suppression of protein kinase C theta contributes to enhanced myogenesis in vitro via IRS1 and ERK1/2 phosphorylation." dans: BMC cell biology, Vol. 14, pp. 39, (2013) (PubMed).

Van Kolen, Slegers: "Atypical PKCzeta is involved in RhoA-dependent mitogenic signaling by the P2Y(12) receptor in C6 cells." dans: The FEBS journal, Vol. 273, Issue 8, pp. 1843-54, (2006) (PubMed).

Xu, Chaudhary, Olland, Wolfrom, Czerwinski, Malakian, Lin, Stahl, Joseph-McCarthy, Benander, Fitz, Greco, Somers, Mosyak: "Catalytic domain crystal structure of protein kinase C-theta (PKCtheta)." dans: The Journal of biological chemistry, Vol. 279, Issue 48, pp. 50401-9, (2004) (PubMed).

Thebault, Ochoa-Garay: "Characterization of TCR-induced phosphorylation of PKCtheta in primary murine lymphocytes." dans: Molecular immunology, Vol. 40, Issue 13, pp. 931-42, (2004) (PubMed).

Sun, Mao, Rao et al.: "Association of CBFA2 mutation with decreased platelet PKC-theta and impaired receptor-mediated activation of GPIIb-IIIa and pleckstrin phosphorylation: proteins regulated by CBFA2 play a role in ..." dans: Blood, Vol. 103, Issue 3, pp. 948-54, (2004) (PubMed).

Burchfield, Lennard, Narasimhan, Hughes, Wasinger, Corthals, Okuda, Kondoh, Biden, Schmitz-Peiffer: "Akt mediates insulin-stimulated phosphorylation of Ndrg2: evidence for cross-talk with protein kinase C theta." dans: The Journal of biological chemistry, Vol. 279, Issue 18, pp. 18623-32, (2004) (PubMed).

Zhang, Anastasiadis, Liu, Thompson, Fields: "Protein kinase C (PKC) betaII induces cell invasion through a Ras/Mek-, PKC iota/Rac 1-dependent signaling pathway." dans: The Journal of biological chemistry, Vol. 279, Issue 21, pp. 22118-23, (2004) (PubMed).

Carrasco, Merida: "Diacylglycerol-dependent binding recruits PKCtheta and RasGRP1 C1 domains to specific subcellular localizations in living T lymphocytes." dans: Molecular biology of the cell, Vol. 15, Issue 6, pp. 2932-42, (2004) (PubMed).

Zhang, Keane, Zhu, Sharma, Rozengurt, Strieter, Dubinett, Huang: "Interleukin-7 and transforming growth factor-beta play counter-regulatory roles in protein kinase C-delta-dependent control of fibroblast collagen synthesis in pulmonary fibrosis." dans: The Journal of biological chemistry, Vol. 279, Issue 27, pp. 28315-9, (2004) (PubMed).

Synonymes et noms alternatifs relatifs à PKC theta

protein kinase C theta (PRKCQ), protein kinase C eta (PRKCH), protein kinase C, theta (Prkcq), protein kinase C theta (Prkcq), A130035A12Rik, AW494342, nPKC-theta, PKC-0, PKC-theta, Pkcq, PKCtheta, PRKCT

Protein level used designations for PKC theta

  • protein kinase C theta type
  • PKC theta
  • nPKC-theta
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