PRKAA1/PRKAA2 Produits
(AMPK1/AMPK2)
Catégories
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008].
antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.
PRKAA1/PRKAA2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Monkey, Mouse, Rat
Application
WB, ELISA, IHC (p), IF
Validations
- (3)
N° du produit
ABIN7250794
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Pig, Rat, Sheep
Application
WB, ELISA, IF (cc), IHC (p), FACS, IF (p), IHC (fro)
Validations
- (4)
- (1)
N° du produit
ABIN752368
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF
Validations
- (1)
N° du produit
ABIN1842476
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PRKAA1/PRKAA2
: "PDGFR Signaling Mediates Hyperproliferation and Fibrotic Responses of Subsynovial Connective Tissue Cells in Idiopathic Carpal Tunnel Syndrome." dans: Scientific reports, Vol. 7, Issue 1, pp. 16192, (2019) (PubMed).: "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." dans: Chemosphere, Vol. 194, pp. 147-157, (2018) (PubMed).
: "Regulation of steroid hormones and energy status with cysteamine and its effect on spermatogenesis." dans: Toxicology and applied pharmacology, Vol. 313, pp. 149-158, (2016) (PubMed).
: "Hydrogen Sulfide and/or Ammonia Reduces Spermatozoa Motility through AMPK/AKT Related Pathways." dans: Scientific reports, Vol. 6, pp. 37884, (2016) (PubMed).
: "Mitochondrial biogenesis fails in secondary biliary cirrhosis in rats leading to mitochondrial DNA depletion and deletions." dans: American journal of physiology. Gastrointestinal and liver physiology, Vol. 301, Issue 1, pp. G119-27, (2011) (PubMed).
: "Global phosphoproteome of HT-29 human colon adenocarcinoma cells." dans: Journal of proteome research, Vol. 4, Issue 4, pp. 1339-46, (2005) (PubMed).
: "Identification of phosphorylation sites in AMP-activated protein kinase (AMPK) for upstream AMPK kinases and study of their roles by site-directed mutagenesis." dans: The Journal of biological chemistry, Vol. 278, Issue 31, pp. 28434-42, (2003) (PubMed).
Synonymes et noms alternatifs relatifs à PRKAA1/PRKAA2
protein kinase AMP-activated catalytic subunit alpha 2 (PRKAA2), protein kinase AMP-activated catalytic subunit alpha 2 (Prkaa2), protein kinase, AMP-activated, alpha 2 catalytic subunit (Prkaa2), 2310008I11Rik, A830082D05, AMPK, Ampk, AMPK2, AMPKa2, Ampka2, AMPKalpha2, PRKAAProtein level used designations for PRKAA1/PRKAA2
- 5'-AMP-activated protein kinase catalytic subunit alpha-2
- 5'-AMP-activated protein kinase, catalytic alpha-2 chain
- ACACA kinase
- AMPK subunit alpha-2
- AMPK-alpha-2 chain
- HMGCR kinase
- acetyl-CoA carboxylase kinase
- hydroxymethylglutaryl-CoA reductase kinase
- AMP-activated protein kinase
- AMPK alpha-2 chain
- AMP-activated protein kinase alpha-2 variant B
Vous êtes ici:
