PRKG1 Produits
(Protein Kinase, CGMP-Dependent, Type I (PRKG1))
Catégories
Mammals have three different isoforms of cyclic GMP-dependent protein kinase (Ialpha, Ibeta, and II). These PRKG isoforms act as key mediators of the nitric oxide/cGMP signaling pathway and are important components of many signal transduction processes in diverse cell types. This PRKG1 gene on human chromosome 10 encodes the soluble Ialpha and Ibeta isoforms of PRKG by alternative transcript splicing. A separate gene on human chromosome 4, PRKG2, encodes the membrane-bound PRKG isoform II. The PRKG1 proteins play a central role in regulating cardiovascular and neuronal functions in addition to relaxing smooth muscle tone, preventing platelet aggregation, and modulating cell growth. This gene is most strongly expressed in all types of smooth muscle, platelets, cerebellar Purkinje cells, hippocampal neurons, and the lateral amygdala. Isoforms Ialpha and Ibeta have identical cGMP-binding and catalytic domains but differ in their leucine/isoleucine zipper and autoinhibitory sequences and therefore differ in their dimerization substrates and kinase enzyme activity. [provided by RefSeq, Sep 2011].
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Catégories PRKG1 en vedette
PRKG1 Anticorps
High quality antibodies with extensive validation data.
PRKG1 Kits ELISA
Reliable ELISA kits for a wide range of species.
PRKG1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PRKG1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (1)
- (4)
N° du produit
ABIN392536
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
N° du produit
ABIN562400
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (3)
N° du produit
ABIN562402
Quantité
100 μg
Fiche technique
Fiche technique
PRKG1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969729
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6958936
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6958937
Quantité
96 tests
Fiche technique
Fiche technique
PRKG1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Insect cells (Sf21)
Validations
- (2)
N° du produit
ABIN5570613
Quantité
5 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1316297
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1316295
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PRKG1
: "A molecular mechanism for therapeutic effects of cGMP-elevating agents in pulmonary arterial hypertension." dans: The Journal of biological chemistry, Vol. 288, Issue 23, pp. 16557-66, (2013) (PubMed).Synonymes et noms alternatifs relatifs à PRKG1
protein kinase, cGMP-dependent, type Ia (prkg1a), protein kinase, cGMP-dependent, type I (PRKG1), protein kinase, cGMP-dependent, type I (prkg1), protein kinase, cGMP-dependent, type 1 (Prkg1), protein kinase, cGMP-dependent, type I (Prkg1), 1, AW125416, cGK, cGk1, cGK 1, cGK1, cGKI, CGKI, cGKI-alpha, cGKI-BETA, cGKI-beta, Gm19690, PKG, Pkgi, prkg1, PRKG1B, Prkg1b, Prkg1beta, PRKGR1B, Prkgr1b, zgc:63955Protein level used designations for PRKG1
- cGMP-dependent protein kinase 1
- protein kinase, cGMP-dependent, type I
- cGMP-dependent protein kinase 1, beta isozyme
- cGMP-dependent protein kinase I alpha
- cGK I alpha
- cGMP-dependent protein kinase 1-like
- cGMP dependent protein kinase type 1
- protein kinase, cGMP-dependent, regulatory, type I, beta
- CGK 1 alpha
- cGK 1 beta
- cGK1
- cGKI-alpha
- cGMP-dependent protein kinase 1, alpha isozyme
- cGMP-dependent protein kinase I
- cGK 1
- PKG1 alpha
- cGMP-dependent protein kinase type 1 alpha
- cGMP-dependent protein kinase type I beta
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