PRKAB1 Produits
(Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))
Catégories
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. [provided by RefSeq, Jul 2008].
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Catégories PRKAB1 en vedette
PRKAB1 Anticorps
High quality antibodies with extensive validation data.
PRKAB1 Kits ELISA
Reliable ELISA kits for a wide range of species.
PRKAB1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PRKAB1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
N° du produit
ABIN7269654
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro)
Validations
- (4)
N° du produit
ABIN683068
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Mouse, Rat
Application
ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (4)
N° du produit
ABIN737901
Quantité
100 μL
Fiche technique
Fiche technique
PRKAB1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969728
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969727
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6958933
Quantité
96 tests
Fiche technique
Fiche technique
PRKAB1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124659
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1316211
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7280002
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PRKAB1
: "Regulation of AMPK-related glycolipid metabolism imbalances redox homeostasis and inhibits anchorage independent growth in human breast cancer cells." dans: Redox biology, Vol. 17, pp. 180-191, (2018) (PubMed).: "Reduced expression of AMPK-β1 during tumor progression enhances the oncogenic capacity of advanced ovarian cancer." dans: Molecular cancer, Vol. 13, pp. 49, (2014) (PubMed).
: "The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor." dans: The Journal of biological chemistry, Vol. 282, Issue 41, pp. 30107-19, (2007) (PubMed).
: "C75, a fatty acid synthase inhibitor, modulates AMP-activated protein kinase to alter neuronal energy metabolism." dans: The Journal of biological chemistry, Vol. 279, Issue 5, pp. 3817-27, (2004) (PubMed).
: "AMP-activated protein kinase plays a role in the control of food intake." dans: The Journal of biological chemistry, Vol. 279, Issue 13, pp. 12005-8, (2004) (PubMed).
: "AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus." dans: Nature, Vol. 428, Issue 6982, pp. 569-74, (2004) (PubMed).
: "Posttranslational modifications of the 5'-AMP-activated protein kinase beta1 subunit." dans: The Journal of biological chemistry, Vol. 272, Issue 39, pp. 24475-9, (1997) (PubMed).
: "Phosphorylation of rat muscle acetyl-CoA carboxylase by AMP-activated protein kinase and protein kinase A." dans: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 82, Issue 1, pp. 219-25, (1997) (PubMed).
: "Isoform-specific purification and substrate specificity of the 5'-AMP-activated protein kinase." dans: The Journal of biological chemistry, Vol. 271, Issue 45, pp. 28445-50, (1996) (PubMed).
: "Characterization of AMP-activated protein kinase beta and gamma subunits. Assembly of the heterotrimeric complex in vitro." dans: The Journal of biological chemistry, Vol. 271, Issue 17, pp. 10282-90, (1996) (PubMed).
Synonymes et noms alternatifs relatifs à PRKAB1
protein kinase AMP-activated non-catalytic subunit beta 1 (PRKAB1), protein kinase, AMP-activated, beta 1 non-catalytic subunit (Prkab1), protein kinase AMP-activated non-catalytic subunit beta 1 (Prkab1), protein kinase, AMP-activated, beta 1 non-catalytic subunit S homeolog (prkab1.S), protein kinase, AMP-activated, beta 1 non-catalytic subunit (prkab1), protein kinase, AMP-activated, beta 1 non-catalytic subunit, b (prkab1b), protein kinase, AMP-activated, beta 1 non-catalytic subunit, a (prkab1a), 1300015D22Rik, AMPK, AU021155, E430008F22, HAMPKb, MGC82489, prkab1, wu:fk93d05, wu:fw87e09, zgc:56652, zgc:76975, zgc:92228Protein level used designations for PRKAB1
- 5'-AMP-activated protein kinase beta-1 subunit
- 5'-AMP-activated protein kinase subunit beta-1
- AMP-activated protein kinase beta subunit
- AMPK beta -1 chain
- AMPK beta 1
- AMPK subunit beta-1
- AMPKb
- protein kinase, AMP-activated, noncatalytic, beta-1
- 5'-AMP-activated protein kinase 40 kDa subunit
- 5'-AMP-activated protein kinase, beta subunit
- 5-AMP-activated protein kinase beta subunit
- AMPK beta-1 chain
- 5'AMP-activated protein kinase beta-1 non-catalytic subunit
- protein kinase, AMP-activated, beta 1 non-catalytic subunit
- AMP-activated protein kinase beta 1 non-catalytic subunit
- AMPK-activated protein kinase beta-1 subunit
- protein kinase, AMP-activated, beta 1 non-catalytic subunit, b
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