PRKAA2 Produits
(Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))
Catégories
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008].
antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.
Catégories PRKAA2 en vedette
PRKAA2 Anticorps
High quality antibodies with extensive validation data.
PRKAA2 Kits ELISA
Reliable ELISA kits for a wide range of species.
PRKAA2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PRKAA2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, RNAi, PLA
Validations
- (6)
N° du produit
ABIN519168
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, FACS
Validations
- (7)
N° du produit
ABIN5611223
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IF, IHC (p), IP, ICC
Validations
- (3)
- (5)
N° du produit
ABIN2855639
Quantité
100 μL
Fiche technique
Fiche technique
PRKAA2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969726
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1119510
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Pig
Analytical Method
Validations
N° du produit
ABIN1119511
Quantité
96 tests
Fiche technique
Fiche technique
PRKAA2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124658
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1316209
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1783060
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PRKAA2
: "Metformin protects against PM2.5-induced lung injury and cardiac dysfunction independent of AMP-activated protein kinase α2." dans: Redox biology, Vol. 28, pp. 101345, (2020) (PubMed).: "The evidence of metabolic-improving effect of metformin in Ay/a mice with genetically-induced melanocortin obesity and the contribution of hypothalamic mechanisms to this effect." dans: PLoS ONE, Vol. 14, Issue 3, pp. e0213779, (2019) (PubMed).
: "Alternative polyadenylation drives genome-to-phenome information detours in the AMPKα1 and AMPKα2 knockout mice." dans: Scientific reports, Vol. 8, Issue 1, pp. 6462, (2018) (PubMed).
: "Metformin ameliorates hepatic steatosis and improves the induction of autophagy in HFD‑induced obese mice." dans: Molecular medicine reports, Vol. 16, Issue 1, pp. 680-686, (2017) (PubMed).
: "LncRNA NBR2 engages a metabolic checkpoint by regulating AMPK under energy stress." dans: Nature cell biology, Vol. 18, Issue 4, pp. 431-42, (2016) (PubMed).
: "AMP-activated protein kinase stimulates Warburg-like glycolysis and activation of satellite cells during muscle regeneration." dans: The Journal of biological chemistry, Vol. 290, Issue 44, pp. 26445-56, (2015) (PubMed).
: "High CO2 levels cause skeletal muscle atrophy via AMP-activated kinase (AMPK), FoxO3a protein, and muscle-specific Ring finger protein 1 (MuRF1)." dans: The Journal of biological chemistry, Vol. 290, Issue 14, pp. 9183-94, (2015) (PubMed).
: "Identification of a novel AMPK-PEA15 axis in the anoikis-resistant growth of mammary cells." dans: Breast cancer research : BCR, Vol. 16, Issue 4, pp. 420, (2015) (PubMed).
: "Activation of AMP-activated protein kinase α2 by nicotine instigates formation of abdominal aortic aneurysms in mice in vivo." dans: Nature medicine, Vol. 18, Issue 6, pp. 902-10, (2012) (PubMed).
: "Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK." dans: Nature, Vol. 482, Issue 7384, pp. 251-5, (2012) (PubMed).
Synonymes et noms alternatifs relatifs à PRKAA2
protein kinase AMP-activated catalytic subunit alpha 2 (PRKAA2), protein kinase AMP-activated catalytic subunit alpha 2 (Prkaa2), protein kinase, AMP-activated, alpha 2 catalytic subunit (Prkaa2), protein kinase, AMP-activated, alpha 2 catalytic subunit S homeolog (prkaa2.S), protein kinase, AMP-activated, alpha 2 catalytic subunit (prkaa2), 2310008I11Rik, A830082D05, AMPK, Ampk, ampk, AMPK2, ampk2, AMPKa2, Ampka2, AMPKA2, AMPKalpha2, PRKAA, prkaa, prkaa1, PRKAA2Protein level used designations for PRKAA2
- 5'-AMP-activated protein kinase catalytic subunit alpha-2
- 5'-AMP-activated protein kinase, catalytic alpha-2 chain
- ACACA kinase
- AMPK subunit alpha-2
- AMPK-alpha-2 chain
- HMGCR kinase
- acetyl-CoA carboxylase kinase
- hydroxymethylglutaryl-CoA reductase kinase
- AMP-activated protein kinase
- AMPK alpha-2 chain
- AMP-activated protein kinase alpha-2 variant B
- AMP-activated protein kinase alpha 2
- protein kinase AMP-activated alpha 2 catalytic subunit
- SNF1-like protein AMPK
- 5'-AMP-activated protein kinase alpha-2 catalytic subunit
- AMPKalpha2
- ampka2
- AMP-activated protein kinase alpha 2 catalytic subunit
- protein kinase, AMP-activated, alpha 2 catalytic subunit
- AMPK-activated protein kinase alpha-2 subunit
Vous êtes ici:
