Alfa-1 Antitrypsin Protéine

N° du produit ABIN1042573

Détail du produit

Antigène: Alfa-1 Antitrypsin

Type de proteíne: Recombinant

Origine: Humain

Source: Rice (Oryza sativa)

Attributs du produit: Activity: 3-5mg OsrAATwill inhibit 1mg PPE with an activity of 10.8 units per mg protein
Formulation: Lyophilized from a 200 myL sterile-filtered solution added Osr HSA for protection.

Pureté: > 95 % , SDS Page

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS pH7.0

Stock: -20 °C

Référence

Zhang, Shi, Jiang, Stupak, Ou, Qiu, An, Li, Yang: "Expression and characterization of recombinant human alpha-antitrypsin in transgenic rice seed." dans: Journal of biotechnology, Vol. 164, Issue 2, pp. 300-8, (2013) (PubMed).

Détail du antigène

Antigène: Alfa-1 Antitrypsin

Synonymes: A1A Protein, A1AT Protein, AAT Protein, PI Protein, PI1 Protein, PRO2275 Protein, alpha1AT Protein, serpin family A member 1 Protein, SERPINA1 Protein

Sujet: OsrAAT is a Human Recombinant protein produced in Rice, which is a single, non-glycosylated polypeptidechain containing 384 amino acids and has a molecular mass of 43.1 kDa. OsrAAT is a serine protease inhibitor which its targets include elastase, plasmin, collagenase, thrombin, leucocytic proteases, trypsin, chymotrypsin, and plasminogen activator. In its absence, neutrophil elastase is free to break down elastin, which contributes to the elasticity of the lungs, resulting in respiratory complications such as emphysema, or COPD (chronic obstructive pulmonary disease) in adults and cirrhosis in adults or children. The OsrAAT protein is purified by chromatographic techniques.