Cathepsin E Protein (CTSE) (AA 20-396) (His tag)

N° du produit ABIN1096239

Détail du produit

Antigène: Cathepsin E (CTSE)

Type de proteíne: Recombinant

Attributs du protein: AA 20-396

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette Cathepsin E protéine est marqué à la His tag.

Fonction: Recombinant Human Cathepsin E/CTSE (C-6His)

Séquence: SLHRVPLRRH PSLKKKLRAR SQLSEFWKSH NLDMIQFTES CSMDQSAKEP LINYLDMEYF GTISIGSPPQ NFTVIFDTGS SNLWVPSVYC TSPACKTHSR FQPSQSSTYS QPGQSFSIQY GTGSLSGIIG ADQVSVEGLT VVGQQFGESV TEPGQTFVDA EFDGILGLGY PSLAVGGVTP VFDNMMAQNL VDLPMFSVYM SSNPEGGAGS ELIFGGYDHS HFSGSLNWVP VTKQAYWQIA LDNIQVGGTV MFCSEGCQAI VDTGTSLITG PSDKIKQLQN AIGAAPVDGE YAVECANLNV MPDVTFTING VPYTLSPTAY TLLDFVDGMQ FCSSGFQGLD IHPPAGPLWI LGDVFIRQFY SVFDRGNNRV GLAPAVPVDH HHHHH

Attributs du produit:

Recombinant Human Cathepsin E/CTSE (C-6His)

Specific Activity is greater than 350pmol/min/ugMeasured by its ability to cleave the fluorogenic peptide substrate, Mca-PLGL-Dpa-AR-NH2

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM MES, 150 mM NaCl, pH 5.5.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: 4 °C/-20 °C/-80 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: Cathepsin E (CTSE)

Autre désignation: Cathepsin E (CTSE Produits)

Synonymes: CATE Protein, A430072O03Rik Protein, C920004C08Rik Protein, CE Protein, CatE Protein, CEA Protein, CEB Protein, Ctsea Protein, CTSE Protein, ce1 Protein, ce2 Protein, cate Protein, CE1 Protein, ce1-A Protein, ctse Protein, CE2 Protein, ce2-A Protein, cathepsin E Protein, cathepsin E L homeolog Protein, cathepsin E S homeolog Protein, CTSE Protein, Ctse Protein, TP03_0056 Protein, Smp_184930 Protein, ctse Protein, ctse.L Protein, ctse.S Protein

Sujet: Recombinant Human Cathepsin E is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Ser20-Pro396) of Human CTSE fused with a polyhistidine tag at the C-terminus.
Cathepsin E (CTSE) is a gastric aspartyl protease that functions as a disulfide-linked homodimer. It is a member of the Peptidase C1 family, and has a specificity similar to that of Pepsin A and Cathepsin D. CTSE is localized to the endoplasmic reticulum and Golgi apparatus, while the mature enzyme is localized to the endosome. It is expressed abundantly in the stomach, the Clara cells of the lung and activated B-lymphocytes, and at lower levels in lymph nodes, skin and spleen. CTSE is an intracellular proteinase that have a role in immune function, activation-induced lymphocyte depletion in the thymus, neuronal degeneration and glial cell activation in the brain. Futhermore, it probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation.

Poids moléculaire: 41.78 kDa

UniProt: P14091