CHI3L1 Protein (AA 22-383) (His tag)

N° du produit ABIN1096380

Détail du produit

Antigène: CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))

Type de proteíne: Recombinant

Attributs du protein: AA 22-383

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette CHI3L1 protéine est marqué à la His tag.

Fonction: Recombinant Human Chitinase-3-Like Protein 1/CHI3L1 (C-6His)

Séquence: YKLVCYYTSW SQYREGDGSC FPDALDRFLC THIIYSFANI SNDHIDTWEW NDVTLYGMLN TLKNRNPNLK TLLSVGGWNF GSQRFSKIAS NTQSRRTFIK SVPPFLRTHG FDGLDLAWLY PGRRDKQHFT TLIKEMKAEF IKEAQPGKKQ LLLSAALSAG KVTIDSSYDI AKISQHLDFI SIMTYDFHGA WRGTTGHHSP LFRGQEDASP DRFSNTDYAV GYMLRLGAPA SKLVMGIPTF GRSFTLASSE TGVGAPISGP GIPGRFTKEA GTLAYYEICD FLRGATVHRI LGQQVPYATK GNQWVGYDDQ ESVKSKVQYL KDRQLAGAMV WALDLDDFQG SFCGQDLRFP LTNAIKDALA ATVDHHHHHH

Attributs du produit: Recombinant Human Chitinase-3-Like Protein 1/CHI3L1 produced by transfected human cells is a secreted protein with sequence (Tyr22-Thr383) of Human CHI3L1 fused with a polyhistidine tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: 4 °C/-20 °C/-80 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 3 months

Détail du antigène

Antigène: CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))

Autre désignation: chitinase-3-like-1 (CHI3L1 Produits)

Synonymes: AW208766 Protein, Brp39 Protein, Gp39 Protein, ASRT7 Protein, CGP-39 Protein, GP-39 Protein, GP39 Protein, HC-gp39 Protein, HCGP-3P Protein, YKL-40 Protein, YKL40 Protein, YYL-40 Protein, hCGP-39 Protein, GP38K Protein, CLP-1 Protein, SPC-40 Protein, SPS-40 Protein, Chil1 Protein, BP40 Protein, MGP-40 Protein, chitinase-like 1 Protein, chitinase 3 like 1 Protein, chitinase 3-like 1 (cartilage glycoprotein-39) Protein, Chil1 Protein, CHI3L1 Protein, Chi3l1 Protein

Sub Type: Fusionprotein

Classe de substances: Viral Protein

Sujet: Chitinase-3-Like Protein 1 (CHI3L1) belongs to the glycosyl hydrolase 18 family. CHI3L1 is expressed in activated macrophages, articular chondrocytes, synovial cells as well as in liver. It lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. CHI3L1 is thought to play a role in defense against pathogens, or in tissue remodeling, and in the capacity of cells to respond to and cope with changes in their environment. In addition, CHI3L1 is associated with susceptibility to asthma-related traits type 7 (ASRT7) which assessed by methacholine challenge test, serum IgE levels, atopy, and atopic dermatitis.
Alternative Names: Chitinase-3-Like protein 1, 39 kDa Synovial Protein, Cartilage Glycoprotein 39, CGP-39, GP-39, hCGP-39, YKL-40, CHI3L1

Poids moléculaire: 51.53 kDa

UniProt: P36222