LSM4 Protein (AA 1-139) (His tag)

N° du produit ABIN1690971

Détail du produit

Antigène: LSM4 (LSM4 Homolog, U6 Small Nuclear RNA Associated (LSM4))

Type de proteíne: Recombinant

Attributs du protein: AA 1-139

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette LSM4 protéine est marqué à la His tag.

Fonction: Recombinant Human U6 snRNA-Associated Sm-Like Protein LSm4/LSM4 (N-6His)

Séquence: MGSSHHHHHH SSGLVPRGSH MLPLSLLKTA QNHPMLVELK NGETYNGHLV SCDNWMNINL REVICTSRDG DKFWRMPECY IRGSTIKYLR IPDEIIDMVK EEVVAKGRGR GGLQQQKQQK GRGMGGAGRG VFGGRGRGGI PGTGRGQPEK KPGRQAGKQ

Attributs du produit: Recombinant Human U6 snRNA-Associated Sm-Like Protein LSm4/LSM4 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Gln139) of Human LSM4 fused with a His tag at the N-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 1 mM DTT, pH 8.0 .

Agent conservateur: Dithiothreitol (DTT)

Précaution d'utilisation: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: 4 °C/-20 °C/-80 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 3 months

Détail du antigène

Antigène: LSM4 (LSM4 Homolog, U6 Small Nuclear RNA Associated (LSM4))

Autre désignation: U6 SnRNA-Associated Sm-Like Protein LSm4 (LSM4 Produits)

Synonymes: GRP Protein, YER112W Protein, LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated S homeolog Protein, LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated Protein, lsm4.S Protein, LSM4 Protein, Lsm4 Protein

Sub Type: Fusionprotein

Sujet: U6 snRNA-associated Sm-like protein LSm4 (LSM4) is a member of the snRNP Sm proteins family. Sm-like proteins contain the Sm sequence motif and are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing. LSM4 forms a heteromer with a donut shape. The complexes are involved in various steps of RNA metabolism. LSM4 binds specifically to the 3-terminal U-tract of U6 snRNA. LSM4 contributes RNA protein interactions and structural changes which are essential during ribosomal subunit assembly.
Alternative Names: U6 snRNA-Associated Sm-Like Protein LSm4, Glycine-Rich Protein, GRP, LSM4

Poids moléculaire: 17.5 kDa

UniProt: Q9Y4Z0