RTN4RL1 Protein (AA 25-419) (His tag)

N° du produit ABIN1097230

Détail du produit

Antigène: RTN4RL1 (Reticulon 4 Receptor-Like 1 (RTN4RL1))

Type de proteíne: Recombinant

Attributs du protein: AA 25-419

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette RTN4RL1 protéine est marqué à la His tag.

Fonction: Recombinant Human Nogo-66 Receptor-Related 3/NgR3/RTN4RL1 (C-6His)

Séquence: CPRDCVCYPA PMTVSCQAHN FAAIPEGIPV DSERVFLQNN RIGLLQPGHF SPAMVTLWIY SNNITYIHPS TFEGFVHLEE LDLGDNRQLR TLAPETFQGL VKLHALYLYK CGLSALPAGV FGGLHSLQYL YLQDNHIEYL QDDIFVDLVN LSHLFLHGNK LWSLGPGTFR GLVNLDRLLL HENQLQWVHH KAFHDLRRLT TLFLFNNSLS ELQGECLAPL GALEFLRLNG NPWDCGCRAR SLWEWLQRFR GSSSAVPCVS PGLRHGQDLK LLRAEDFRNC TGPASPHQIK SHTLTTTDRA ARKEHHSPHG PTRSKGHPHG PRPGHRKPGK NCTNPRNRNQ ISKAGAGKQA PELPDYAPDY QHKFSFDIMP TARPKRKGKC ARRTPIRAPS GVQQAVDHHH HHH

Attributs du produit: Recombinant Human Nogo-66 Receptor-Related Protein 3/NgR3 produced by transfected human cells is a secreted protein with sequence (Cys25-Ala419) of Human RTN4RL1 fused with a polyhistidine tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 5 % Threhalose, pH 7.2.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: 4 °C/-20 °C/-80 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 3 months

Détail du antigène

Antigène: RTN4RL1 (Reticulon 4 Receptor-Like 1 (RTN4RL1))

Autre désignation: ngr3 (RTN4RL1 Produits)

Synonymes: NgRH2a Protein, rtn4rl1 Protein, RTN4RL1 Protein, MGC146480 Protein, Ngr3 Protein, Ngrh2 Protein, Ngrl2 Protein, NGRH2 Protein, NgR3 Protein, reticulon 4 receptor-like 1b Protein, reticulon 4 receptor like 1 Protein, reticulon 4 receptor-like 1 Protein, rtn4rl1b Protein, RTN4RL1 Protein, rtn4rl1 Protein, Rtn4rl1 Protein

Sub Type: Fusionprotein

Sujet: Nogo-66 Receptor-Related Protein 3 (NgR3) has primary structures with NgR2 (NgRH1, NgRL3) and biochemical properties that are homologous to Nogo-66 receptor (NgR), and constitute a novel neuronal receptor protein family. NgR is GPI-anchored and contains eight leucine-rich repeats (LRR), it is the neuronal receptor for the myelin- associated proteins Nogo-A, OMgp (oligodendrocyte myelin glycoprotein), and MAG (myelin-associated glycoprotein) and mediates the inhibition of CNS axonal regeneration both in vitro and in vivo. NgR2 and NgR3 have similar structure and distinct but overlapping expression versus NgR. NgR2 can be metalloproteinase-cleaved to release a soluble ectodomain. NgR2 has also been shown to bind MAG, but ligands for NgR3 have not yet been determined. Mature huaman NgR3 shares 88%, 88%, 48% and 44% amino acid identity with mature mouse NgR3, rat NgR3, human NgRH1 and NgR, repectively.
Alternative Names: Reticulon-4 Receptor-Like 1, Nogo Receptor-Like 2, Nogo-66 Receptor Homolog 2, Nogo-66 Receptor-Related Protein 3, NgR3, RTN4RL1, NGRH2, NGRL2

Poids moléculaire: 45.49 kDa

UniProt: Q86UN2