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BCAS2 Protein (AA 2-225) (His tag,T7 tag)

BCAS2 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN1097391
  • Antigène Voir toutes BCAS2 Protéines
    BCAS2 (Breast Carcinoma Amplified Sequence 2 (BCAS2))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 2-225
    Origine
    • 7
    • 1
    • 1
    Humain
    Source
    • 5
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette BCAS2 protéine est marqué à la His tag,T7 tag.
    Fonction
    Recombinant Human BCAS2/DAM1 (C-6His, N-T7 tag)
    Séquence
    MASMTGGQQM GRGSMAGTGL VAGEVVVDAL PYFDQGYEAP GVREAAAALV EEETRRYRPT KNYLSYLTAP DYSAFETDIM RNEFERLAAR QPIELLSMKR YELPAPSSGQ KNDITAWQEC VNNSMAQLEH QAVRIENLEL MSQHGCNAWK VYNENLVHMI EHAQKELQKL RKHIQDLNWQ RKNMQLTAGS KLREMESNWV SLVSKNYEIE RTIVQLENEI YQIKQQHGEA NKENIRQDFL EHHHHHH
    Attributs du produit
    Recombinant Human Breast Carcinoma-Amplified Sequence 2/BCAS2 is produced by our E. coli expression system. The target protein is expressed with sequence (Ala2-Phe225) of Human BCAS2 fused with a 6His tag at the C-terminus.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    Stérilité
    0.2 μm filtered
    niveau d'endotoxine
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 200 mM NaCl, 2 mM DTT, pH 8.0.
    Agent conservateur
    Dithiothreitol (DTT)
    Précaution d'utilisation
    This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Stock
    4 °C/-20 °C/-80 °C
    Stockage commentaire
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Date de péremption
    3 months
  • Antigène
    BCAS2 (Breast Carcinoma Amplified Sequence 2 (BCAS2))
    Autre désignation
    Breast Carcinoma-Amplified Sequence 2/BCAS2 (BCAS2 Produits)
    Synonymes
    DAM1 Protein, SPF27 Protein, Snt309 Protein, 6430539P16Rik Protein, AI132645 Protein, C76366 Protein, C80030 Protein, BCAS2 Protein, cb302 Protein, zgc:101730 Protein, BCAS2, pre-mRNA processing factor Protein, breast carcinoma amplified sequence 2 Protein, breast carcinoma amplified sequence 2 L homeolog Protein, BCAS2 Protein, Bcas2 Protein, bcas2 Protein, bcas2.L Protein, CpipJ_CPIJ003889 Protein
    Sub Type
    Fusionprotein
    Sujet
    Breast Carcinoma-Amplified Sequence 2 (BCAS2) is a member of the SPF27 family. BCAS2 is a nuclear protein and widely expressed in many rtissues. BCAS2 is identified as being overexpressed in various breast cancer cell lines. BCAS2 is a component of the spliceosome, taking part in the removal of introns from mRNA precursors. BCAS2 interacts with estrogen receptor alpha and beta, thyroid hormone receptor beta, peroxisome proliferator-activated receptor gamma. BCAS2 functions as an ER co-activator and is capable of enhancing ER-mediated transcription.
    Alternative Names: Pre-mRNA-Splicing Factor SPF27, Breast Carcinoma-Amplified Sequence 2, DNA Amplified in Mammary Carcinoma 1 Protein, Spliceosome-Associated Protein SPF 27, BCAS2, DAM1
    Poids moléculaire
    28.58 kDa
    UniProt
    O75934
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