PRTN3 Protein (AA 26-249) (His tag)

N° du produit ABIN1097436

Détail du produit

Antigène: PRTN3 (Proteinase 3 (PRTN3))

Type de proteíne: Recombinant

Attributs du protein: AA 26-249

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette PRTN3 protéine est marqué à la His tag.

Fonction: Recombinant Human Proteinase 3/PRTN3/Myeloblastin (C-6His)

Séquence: AEIVGGHEAQ PHSRPYMASL QMRGNPGSHF CGGTLIHPSF VLTAAHCLRD IPQRLVNVVL GAHNVRTQEP TQQHFSVAQV FLNNYDAENK LNDVLLIQLS SPANLSASVA TVQLPQQDQP VPHGTQCLAM GWGRVGAHDP PAQVLQELNV TVVTFFCRPH NICTFVPRRK AGICFGDSGG PLICDGIIQG IDSFVIWGCA TRLFPDFFTR VALYVDWIRS TLRRVDHHHH HH

Attributs du produit: Recombinant Human Proteinase 3/PRTN3 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Ala26-Arg249) of Human PRTN3 fused with a polyhistidine tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 10 mM TrisHCl, 150 mM NaCl, 10 % Glycerol, pH 8.0.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: -80 °C

Stockage commentaire: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Date de péremption: 6 months

Détail du antigène

Antigène: PRTN3 (Proteinase 3 (PRTN3))

Autre désignation: proteinase-3 (PRTN3 Produits)

Synonymes: ela2 Protein, MGC132250 Protein, ACPA Protein, AGP7 Protein, C-ANCA Protein, CANCA Protein, MBN Protein, MBT Protein, NP-4 Protein, NP4 Protein, P29 Protein, PR-3 Protein, PR3 Protein, mPR3 Protein, proteinase 3 L homeolog Protein, proteinase 3 Protein, prtn3.L Protein, PRTN3 Protein, Prtn3 Protein

Sub Type: Fusionprotein

Sujet: Proteinase-3 is a neutral serine proteinase that belongs to the peptidase S1 family and Elastase subfamily. It contains one peptidase S1 domain and it is expressed mainly in neutrophil granulocytes. The primary function of Proteinase-3 is thought to be degradation of extracellular proteins at sites of inflammation, but excessive or prolonged proteolytic activity may cause harmful effects in the body. It is the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis.
Alternative Names: Myeloblastin, AGP7, C-ANCA Antigen, Leukocyte Proteinase 3, PR-3, PR3, Neutrophil Proteinase 4, NP-4, P29, Wegener Autoantigen, PRTN3, MBN

Poids moléculaire: 25.64 kDa

UniProt: P24158