PRSS22 Protein (AA 33-317) (His tag)

N° du produit ABIN1097712

Détail du produit

Antigène: PRSS22 (Protease, serine, 22 (PRSS22))

Type de proteíne: Recombinant

Attributs du protein: AA 33-317

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette PRSS22 protéine est marqué à la His tag.

Fonction: Recombinant Human Tryptase epsilon/Brain-Specific Serine Protease 4/BSSP-4 (C-6His)

Séquence: ARIPVPPACG KPQQLNRVVG GEDSTDSEWP WIVSIQKNGT HHCAGSLLTS RWVITAAHCF KDNLNKPYLF SVLLGAWQLG NPGSRSQKVG VAWVEPHPVY SWKEGACADI ALVRLERSIQ FSERVLPICL PDASIHLPPN THCWISGWGS IQDGVPLPHP QTLQKLKVPI IDSEVCSHLY WRGAGQGPIT EDMLCAGYLE GERDACLGDS GGPLMCQVDG AWLLAGIISW GEGCAERNRP GVYISLSAHR SWVEKIVQGV QLRGRAQGGG ALRAPSQGSG AAARSHHHHH H

Attributs du produit: Recombinant Human Brain-Specific Serine Protease 4/BSSP-4 produced by transfected human cells is a secreted protein with sequence(Ala33-Ser317) of Human BSSP-4 Tryptase fused with a polyhistidine tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM HAc-NaAc, 150 mM NaCl, 10 % Glycerol, pH 4.5.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: -80 °C

Stockage commentaire: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Date de péremption: 6 months

Détail du antigène

Antigène: PRSS22 (Protease, serine, 22 (PRSS22))

Autre désignation: tryptase-epsilon (PRSS22 Produits)

Synonymes: BSSP-4 Protein, hBSSP-4 Protein, 4733401N09Rik Protein, SP001LA Protein, protease, serine, 22 Protein, protease, serine 22 Protein, Prss22 Protein, PRSS22 Protein

Sub Type: Fusionprotein

Sujet: Brain-Specific Serine Protease 4 (BSSP-4) is a serine protease that preferentially cleaves the synthetic substrate H-D-Leu-Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA. BSSP-4 is expressed abundantly in the epithelial cells of the airways, including trachea, esophagus and fetal lung, but scarce in adult lung and expressed at low levels in placenta, pancreas, prostate and thyroid gland. BSSP-4 belongs to the peptidase S1 family and related to trypsin, referentially hydrolyzing substrates after arginine and lysine residues. However, BSSP-4 is less susceptible to inhibition by common trypsin inhibitors such as aprotinin, alpha1-antitrypsin and secretory leukocyte protease inhibitor. BSSP-4 efficiently converts pro-urokinase- type plasminogen activator to its mature, active form.
Alternative Names: Brain-Specific Serine Protease 4, BSSP-4, Serine Protease 22, Serine Protease 26, Tryptase Epsilon, PRSS22, BSSP4, PRSS26

Poids moléculaire: 31.56 kDa

UniProt: Q9GZN4