RANBP1 Protein (His tag)

N° du produit ABIN1098236

Détail du produit

Antigène: RANBP1 (RAN Binding Protein 1 (RANBP1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette RANBP1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Purification: purified by chromatography

Pureté: > 95 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: RAN binding protein 1, HTF9A

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 1 MM DTT, 10% glycerol, 0.1 M NaCl

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: RANBP1 (RAN Binding Protein 1 (RANBP1))

Autre désignation: RANBP1 (RANBP1 Produits)

Synonymes: MGC64314 Protein, zeh1094 Protein, zgc:85649 Protein, hm:zeh1094 Protein, wu:fa96a09 Protein, wu:fj39g07 Protein, HTF9A Protein, Htf9a Protein, RAN binding protein 1 S homeolog Protein, RAN binding protein 1 L homeolog Protein, ran binding protein 1 Protein, RAN binding protein 1 Protein, ran-specific GTPase-activating protein pseudogene Protein, ranbp1.S Protein, ranbp1.L Protein, PVX_090070 Protein, GL50803_16969 Protein, LOC100343953 Protein, ranbp1 Protein, RANBP1 Protein, Ranbp1 Protein

Sujet: RAN binding protein 1, also known as RANBP1, belongs to a family of proteins that bind Ran GTPase which is essential for mRNA processing, nuclear transport, cell cycle control, mitotic spindle assembly, and postmitotic nuclear re-assembly and nuclear architecture maintenance. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). Also, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN. Recombinant human RANBP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 25.8 kDa (225aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

NCBI Accession: NP_002873