GSTA4 Protein (His tag)

N° du produit ABIN1098254

Détail du produit

Antigène: GSTA4 (Glutathione S-Transferase alpha 4 (GSTA4))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette GSTA4 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Purification: purified by chromatography

Pureté: > 95 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: glutathione S-transferase alpha 4, GSTA4-4, GTA4

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer, pH 8.0, 20% glycerol, 2 mM DTT, 100 mM NaCl

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: GSTA4 (Glutathione S-Transferase alpha 4 (GSTA4))

Autre désignation: GSTA4 (GSTA4 Produits)

Synonymes: GSTA4-4 Protein, GTA4 Protein, gsta4-4 Protein, gta4 Protein, tGSTA4 Protein, GST5.7 Protein, mGsta4 Protein, glutathione S-transferase alpha 4 Protein, glutathione S-transferase alpha 4-like Protein, glutathione S-transferase alpha 4 S homeolog Protein, glutathione S-transferase 3 Protein, glutathione S-transferase, alpha 4 Protein, glutathione S-transferase A4 Protein, GSTA4 Protein, Gsta4 Protein, GSTA4L Protein, gsta4 Protein, gsta4.S Protein, LOC100341622 Protein

Sujet: GSTA4, also known as glutathione S-transferase A4, belongs to the GST superfamily. This enzyme is involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. GSTA4 shows very high activity with reactive carbonyl compounds such as alk-2-enals. GSTA4 is highly effective in catalyzing the conjugate addition of reduced glutathione to 4-hydroxynonenal, an important product of peroxidative degradation of arachidonic acid and a commonly used biomarker for oxidative damage in tissue. This enzyme is expressed at a high level in brain, placenta, and skeletal muscle and much lower in lung and liver. Recombinant human GSTA4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 28.3kDa (246aa) confirmed by MALDI-TOF

NCBI Accession: NP_001503