CRYGC Protein (His tag)
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- Antigène Voir toutes CRYGC Protéines
- CRYGC (Crystallin, gamma C (CRYGC))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette CRYGC protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Pureté
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product CRYGC Protéine
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- Commentaires
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Synonyms: Gamma-crystallin C, CCL, CRYG3
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer, pH 8.0, 10% glycerol, 2 mM DTT, 200 mM NaCl
- Stock
- 4 °C
- Stockage commentaire
- Avoid repeated freezing and thawing cycles.
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- Antigène
- CRYGC (Crystallin, gamma C (CRYGC))
- Autre désignation
- CRYGC (CRYGC Produits)
- Synonymes
- Cryg Protein, Cryg3 Protein, Len Protein, CCL Protein, CRYG3 Protein, CTRCT2 Protein, Cryg-5 Protein, ccl Protein, cryg3 Protein, MGC84008 Protein, CRYGC Protein, crystallin, gamma C Protein, crystallin gamma C Protein, crystallin gamma C L homeolog Protein, gamma-crystallin C Protein, Crygc Protein, CRYGC Protein, crygc.L Protein, LOC100069179 Protein
- Sujet
- Gamma-crystallin C, also known as CRYGC, belongs to the beta/gamma-crystallin family. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation. Defects in CRYGC are a cause of cataract autosomal dominant (ADC) and cataract Coppock-like (CCL). Recombinant human CRYGC protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Poids moléculaire
- 23.5kDa (198aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_066269
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