ATPase Inhibitory Factor 1 Protein (ATPIF1) (His tag)

N° du produit ABIN1098337

Détail du produit

Antigène: ATPase Inhibitory Factor 1 (ATPIF1)

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette ATPase Inhibitory Factor 1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Purification: purified by chromatography

Pureté: > 95 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: ATPase inhibitor mitochondrial, ATPI, ATPIP, IP, ATPase Inhibitory Factor 1

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 50% glycerol, 2 mM DTT

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: ATPase Inhibitory Factor 1 (ATPIF1)

Autre désignation: ATPIF1 (ATPIF1 Produits)

Synonymes: ATPI Protein, ATPIP Protein, IP Protein, ATPIF1 Protein, Atpi Protein, If1 Protein, IF1PA Protein, atpi Protein, atpip Protein, IF(1) A Protein, IF1 A Protein, atpif1 Protein, zgc:162207 Protein, IF(1) Protein, IF1 Protein, ATPase inhibitory factor 1 Protein, ATPase inhibitory factor 1 L homeolog Protein, ATPase inhibitory factor 1a Protein, ATPase IV subunit Protein, ATPIF1 Protein, Atpif1 Protein, atpif1.L Protein, atpif1a Protein, atpif1 Protein, LOC100360030 Protein, atpI Protein

Sujet: ATPase inhibitory factor 1, also known as ATPIF1, binds to the C-terminal region of a beta subunit of the F1-ATPase at low pH values and, via interference of the beta and gamma subunit interaction, ATPIF1 regulates the activity of the F1 (the hydrophilic catalytic core), F0 (the membrane embedded protein channel) ATPase. The overexpression of ATPIF1 in several human carcinomas further supports its participation in oncogenesis and provides insight into the altered metabolism of cancer cells, which includes the reprogramming of energetic metabolism toward glycolysis. Recombinant human ATPIF1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 12.2 kDa (106aa), confirmed by MALDI-TOF

NCBI Accession: NP_057395