GCLM Protein (His tag)

N° du produit ABIN1098356

Détail du produit

Antigène: GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette GCLM protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Purification: purified by chromatography

Pureté: > 90 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: Glutamate-cysteine ligase, modifier subunit, GLCLR

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.15 M NaCl

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))

Autre désignation: GCLM (GCLM Produits)

Synonymes: Glclr Protein, GLCLR Protein, id:ibd3182 Protein, wu:fi24c07 Protein, zgc:55903 Protein, AI649393 Protein, Gcmc Protein, glutamate-cysteine ligase regulatory subunit Protein, glutamate cysteine ligase, modifier subunit Protein, glutamate-cysteine ligase modifier subunit Protein, glutamate-cysteine ligase, modifier subunit Protein, glutamate-cysteine ligase, modifier subunit L homeolog Protein, PTRG_09814 Protein, Gclm Protein, GCLM Protein, gclm Protein, gclm.L Protein

Sujet: Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Recombinant human GCLM protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 33.3kDa(298aa), confirmed by MALDI-TOF

NCBI Accession: NP_002052