DTD1 Protein (His tag)

N° du produit ABIN1098471

Détail du produit

Antigène: DTD1 (D-Tyrosyl-tRNA Deacylase 1 Homolog (S. Cerevisiae) (DTD1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette DTD1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Purification: purified by chromatography

Pureté: > 85 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: D-tyrosyl-tRNA deacylase 1, bA379J5.3, bA555E18.1, C20orf88, DUEB, HARS2, pqn-68

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 10% glycerol, 1 MM DTT

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: DTD1 (D-Tyrosyl-tRNA Deacylase 1 Homolog (S. Cerevisiae) (DTD1))

Autre désignation: DTD1 (DTD1 Produits)

Synonymes: 0610006H08Rik Protein, Hars2 Protein, C20orf88 Protein, DUEB Protein, HARS2 Protein, bA379J5.3 Protein, bA555E18.1 Protein, pqn-68 Protein, hars2 Protein, zgc:92657 Protein, D-tyrosyl-tRNA deacylase 1 Protein, Dtd1 Protein, DTD1 Protein, dtd1 Protein

Sujet: DTD1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). It could be a defense mechanism against a harmful effect of D-tyrosine. DTD1 may be a risk factor for aspirin-intolerant asthma (AIA) by catalyzing the hydrolysis of D-tryptophan and interacting with the tyrosyl-tRNA synthetase (tyrRS) enzyme, which promotes a pro-inflammatory phenotype. This protein is localize to the DUE(DNA unwinding element )s of active replication origins. Recombinant human DTD1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 25.9kDa (232aa) confirmed by MALDI-TOF

NCBI Accession: NP_543010