HAX1 Protein (His tag)

N° du produit ABIN1098543

Détail du produit

Antigène: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette HAX1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Purification: purified by chromatography

Pureté: > 80 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: HCLS1 associated protein X-1 isoform a, HCLSBP1, HS1BP1, SCN3

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1 M NaCl

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Autre désignation: HAX1 (HAX1 Produits)

Synonymes: HAX1 Protein, hax1 Protein, HCLSBP1 Protein, HS1BP1 Protein, SCN3 Protein, HAX-1 Protein, Hs1bp1 Protein, HSP1BP-1 Protein, SIG-111 Protein, Silg111 Protein, mHAX-1s Protein, HCLS1 associated protein X-1 Protein, HCLS1 associated X-1 Protein, HAX1 Protein, hax1 Protein, Hax1 Protein

Sujet: HAX1 is known to associate with HS1, a substrate of Src family tyrosine kinases. It also interacts with the product of PKD2, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with F-actin-binding protein, cortactin. It is associated with autosomal recessive severe congenital neutropenia, also known as Kostmann syndrome. Recombinant human HAX1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 33.7 kDa(299aa) confirmed by MALDI-TOF

NCBI Accession: NP_006109

Pathways: Regulation of Actin Filament Polymerization