LITAF Protein (His tag)
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- Antigène Voir toutes LITAF Protéines
- LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette LITAF protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Pureté
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product LITAF Protéine
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- Commentaires
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Synonyms: Lipopolysaccharide-induced TNF-alpha factor, PIG7, SIMPLE
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea, 10% glycerol
- Stock
- 4 °C
- Stockage commentaire
- Avoid repeated freezing and thawing cycles.
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- Antigène
- LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))
- Autre désignation
- LITAF (LITAF Produits)
- Synonymes
- PIG7 Protein, SIMPLE Protein, TP53I7 Protein, EET-1 Protein, Pig7 Protein, TNF-alpha Protein, 3222402J11Rik Protein, C85531 Protein, N4WBP3 Protein, TBX1 Protein, lipopolysaccharide induced TNF factor Protein, lipopolysaccharide-induced TNF factor Protein, LPS-induced TN factor Protein, LITAF Protein, Litaf Protein
- Sujet
- Lipopolysaccharide-induced TNF-alpha factor, also known as LITAF, is a small integral membrane protein of lysosome/late endosome. LITAF mediates the expression of inflammatory cytokines such as TNF-alpha in Lipopolysaccharide-induced processes. LITAF binds to STAT6B, a member of the STAT6 family forming a complex on the TNF-alpha promoter that modulates TNF activity. High levels of expression of LITAF mRNA have been observed predominantly in the placenta, peripheral blood leukocytes, lymph nodes and spleen. Recombinant human LITAF protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Poids moléculaire
- 19.2 kDa (181aa)
- NCBI Accession
- NP_004853
- Pathways
- Cellular Response to Molecule of Bacterial Origin
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