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TDP1 Protein (His tag)

TDP1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
N° du produit ABIN1098766
  • Antigène Voir toutes TDP1 Protéines
    TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
    Type de proteíne
    Recombinant
    Origine
    • 6
    • 3
    • 2
    Humain
    Source
    • 4
    • 2
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette TDP1 protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Pureté
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product TDP1 Protéine
  • Commentaires

    Synonyms: Tyrosyl-DNA phosphodiesterase 1, FLJ11090, SCAN1, Tyr-DNA phosphodiesterase 1, Tyrosyl DNA phosphodiesterase 1, TDP-1

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M urea, 10% glycerol
    Stock
    4 °C
    Stockage commentaire
    Avoid repeated freezing and thawing cycles.
  • Antigène
    TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
    Autre désignation
    TDP1 (TDP1 Produits)
    Synonymes
    2810481F14Rik Protein, 4921509N21Rik Protein, AI838772 Protein, AW493413 Protein, E430034L06Rik Protein, MLZ-501 Protein, SCAN1 Protein, tdp1 Protein, MGC83708 Protein, TDP1 Protein, F8M21.60 Protein, F8M21_60 Protein, tyrosyl-DNA phosphodiesterase 1 Protein, tyrosyl-DNA phosphodiesterase 1 Protein, tyrosyl-DNA Phosphodiesterase (Tdp1) Protein, tyrosyl-DNA phosphodiesterase 1 L homeolog Protein, tyrosyl-DNA phosphodiesterase-like protein Protein, TDP1 Protein, Tc00.1047053511191.10 Protein, Tdp1 Protein, tdp1.L Protein, tdp1 Protein, PTRG_11198 Protein, MCYG_02121 Protein, MGYG_03035 Protein
    Sujet
    Tyrosyl-DNA phosphodiesterase 1, also known as TDP1, is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. Recombinant human TDP1, fused to His-tag at N-terminus, was expressed in E.coli.
    Poids moléculaire
    35.8 kDa (318aa)
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