IGF-like family receptor 1 (IGFLR1) (AA 23-154) protein (Fc Tag)

N° du produit ABIN1344141

Détail du produit

Antigène: IGF-like family receptor 1 (IGFLR1)

Type de proteíne: Recombinant

Attributs du protein: AA 23-154

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Fc Tag

Application: SDS-PAGE (SDS)

Specificité: Binds to its ligand IGFL3 (human) in the subnanomolar range (< 1 ng /mL).

Réactivité croisée: Humain

Attributs du produit: Human IGFLR1 (aa 23-154) is fused at the C-terminus to the Fc portion of human IgG1.

Pureté: >95 % (SDS-PAGE)

niveau d'endotoxine: <0.05EU/μg purified protein (LAL test, Lonza).

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with 50 μL sterile water.

Concentration: Lot specific

Buffer: Lyophilized. Contains PBS.

Stock: 4 °C,-20 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C.

Date de péremption: 6 months

Détail du antigène

Antigène: IGF-like family receptor 1 (IGFLR1)

Autre désignation: IGFLR1 (IGFLR1 Produits)

Sujet: Insulin-growth factor-like gene family is a new family of proteins consisting of four proteins in humans (IGFL1 to 4) and one in mice (mIGFL). mIGFL is expressed in normal skin in mice and further upregulated during inflammation responses in skin or after skin wounding. In human only IGFL1 expression is increased in psoriatic skin samples. mIGFL and human IGFL1 and 3 interact with specificity and high affinity to a novel receptor named IGF-like family receptor 1 (formerly TMEM-149). Analysis of the amino acid sequence of IGFLR1 indicated that this receptor is likely a novel member of the TNF-R family. IGFLR1 is expressed most abundantly on mouse T cells, suggesting that mIGFL and IGFL1 produced in the skin may potentially exert regulatory functions on T cell responses.

Poids moléculaire: ~50kDa (SDS-PAGE)

UniProt: Q9H665