FTO Protein (AA 2-505) (His tag)

N° du produit ABIN1344349

Détail du produit

Antigène: FTO (Fat Mass and Obesity-Associated (FTO))

Type de proteíne: Recombinant

Attributs du protein: AA 2-505

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette FTO protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Réactivité croisée: Humain

Attributs du produit: Human FTO (aa 2-505) is fused at the N-terminus to a His-tag.

Pureté: >90 % (SDS-PAGE)

Stérilité: 0.2 μm filtered

niveau d'endotoxine: <1EU/μg purified protein (LAL test, Lonza).

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.2μm-filtered solution in 55 mM TRIS-Cl, pH 8.2, containing 150 mM NaCl.

Stock: 4 °C,-20 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C.

Date de péremption: 3 months

Détail du antigène

Antigène: FTO (Fat Mass and Obesity-Associated (FTO))

Autre désignation: FTO (FTO Produits)

Synonymes: AW743446 Protein, mKIAA1752 Protein, RGD1305121 Protein, FTO, alpha-ketoglutarate dependent dioxygenase Protein, fat mass and obesity associated Protein, fat mass and obesity associated L homeolog Protein, FTO Protein, Fto Protein, fto.L Protein

Sujet: FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse 'fused toes' mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.

Poids moléculaire: ~65kDa (SDS-PAGE)

UniProt: Q9C0B1