CD44 Protein (CD44) (AA 1-699) (GST tag)

N° du produit ABIN1776516

Détail du produit

Antigène: CD44

Type de proteíne: Recombinant

Attributs du protein: AA 1-699

Origine: Humain

Source: Wheat germ

Purification/Conjugué: Cette CD44 protéine est marqué à la GST tag.

Application: ELISA, Western Blotting (WB), Affinity Purification (AP), Antibody Array (AA)

Fonction: CD44 (Human) Recombinant Protein (P01)

Séquence: MDKFWWHAAW GLCLVPLSLA QIDLNITCRF AGVFHVEKNG RYSISRTEAA DLCKAFNSTL PTMAQMEKAL SIGFETCRYG FIEGHVVIPR IHPNSICAAN NTGVYILTSN TSQYDTYCFN ASAPPEEDCT SVTDLPNAFD GPITITIVNR DGTRYVQKGE YRTNPEDIYP SNPTDDDVSS GSSSERSSTS GGYIFYTFST VHPIPDEDSP WITDSTDRIP ATSTSSNTIS AGWEPNEENE DERDRHLSFS GSGIDDDEDF ISSTISTTPR AFDHTKQNQD WTQWNPSHSN PEVLLQTTTR MTDVDRNGTT AYEGNWNPEA HPPLIHHEHH EEEETPHSTS TIQATPSSTT EETATQKEQW FGNRWHEGYR QTPREDSHST TGTAAASAHT SHPMQGRTTP SPEDSSWTDF FNPISHPMGR GHQAGRRMDM DSSHSTTLQP TANPNTGLVE DLDRTGPLSM TTQQSNSQSF STSHEGLEED KDHPTTSTLT SSNRNDVTGG RRDPNHSEGS TTLLEGYTSH YPHTKESRTF IPVTSAKTGS FGVTAVTVGD SNSNVNRSLS GDQDTFHPSG GSHTTHGSES DGHSHGSQEG GANTTSGPIR TPQIPEWLII LASLLALALI LAVCIAVNSR RRCGQKKKLV INSGNGAVED RKPSGLNGEA SKSQEMVHLV NKESSETPDQ FMTADETRNL QNVDMKIGV

Attributs du produit: Human CD44 full-length ORF ( AAH04372, 1 a.a. - 699 a.a.) recombinant protein with GST-tag at N-terminal.

Purification: in vitro wheat germ expression system

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Preparation method: in vitro, wheat germ expression system
Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

Restrictions: For Research Use only

Stockage

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -80 °C

Stockage commentaire: Best use within three months from the date of receipt of this protein.

Référence

Gebhard, Jain, Nair, Emmons, Argilagos, Koomen, McLaughlin, Hazlehurst: "MTI-101 (cyclized HYD1) binds a CD44 containing complex and induces necrotic cell death in multiple myeloma." dans: Molecular cancer therapeutics, Vol. 12, Issue 11, pp. 2446-58, (2013) (PubMed).

Ababneh, Alshaer, Allozi, Mahafzah, El-Khateeb, Hillaireau, Noiray, Fattal, Ismail: "In vitro selection of modified RNA aptamers against CD44 cancer stem cell marker." dans: Nucleic acid therapeutics, Vol. 23, Issue 6, pp. 401-7, (2013) (PubMed).

Détail du antigène

Antigène: CD44

Autre désignation: CD44 (CD44 Produits)

Synonymes: CDW44 Protein, CSPG8 Protein, ECMR-III Protein, HCELL Protein, HUTCH-I Protein, IN Protein, LHR Protein, MC56 Protein, MDU2 Protein, MDU3 Protein, MIC4 Protein, Pgp1 Protein, AU023126 Protein, AW121933 Protein, AW146109 Protein, HERMES Protein, Ly-24 Protein, Pgp-1 Protein, CD44A Protein, METAA Protein, RHAMM Protein, XCD44 Protein, cd44 Protein, cdw44 Protein, cspg8 Protein, ecmr-iii Protein, hcell Protein, lhr Protein, mc56 Protein, mdu2 Protein, mdu3 Protein, mic4 Protein, mutch-i Protein, pgp1 Protein, CD44 molecule (Indian blood group) Protein, syndecan 4 Protein, CD44 antigen Protein, CD44 molecule (Indian blood group) S homeolog Protein, CD44 Protein, SDC4 Protein, Cd44 Protein, cd44.S Protein

Sujet: Full Gene Name: CD44 Molecule (Indian blood group)
Synonyms: CDW44,CSPG8,ECMR-III,HCELL,IN,LHR,MC56,MDU2,MDU3,MGC10468,MIC4,MUTCH-I,Pgp1

ID gène: 960

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling