FNDC5 Protein (AA 1-137) (GST tag)

N° du produit ABIN1354283

Détail du produit

Antigène: FNDC5 (Fibronectin Type III Domain Containing 5 (FNDC5))

Type de proteíne: Recombinant

Attributs du protein: AA 1-137

Origine: Humain

Source: Wheat germ

Purification/Conjugué: Cette FNDC5 protéine est marqué à la GST tag.

Application: Western Blotting (WB), ELISA, Antibody Array (AA), Affinity Purification (AP)

Fonction: FNDC5 (Human) Recombinant Protein (P01)

Séquence: MLRFIQEVNT TTRSCALWDL EEDTEYIVHV QAISIQGQSP ASEPVLFKTP REAEKMASKN KDEVTMKEMG RNQQLRTGEV LIIVVVLFMW AGVIALFCRQ YDIIKDNEPN NNKEKTKSAS ETSTPEHQGG GLLRSKI

Attributs du produit: Human FNDC5 full-length ORF ( NP_715637.1, 1 a.a. - 137 a.a.) recombinant protein with GST-tag at N-terminal.

Purification: in vitro wheat germ expression system

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Preparation method: in vitro, wheat germ expression system
Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

Restrictions: For Research Use only

Stockage

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -80 °C

Stockage commentaire: Best use within three months from the date of receipt of this protein.

Référence

Elsen, Raschke, Eckel: "Browning of white fat: does irisin play a role in humans?" dans: The Journal of endocrinology, Vol. 222, Issue 1, pp. R25-38, (2014) (PubMed).

Erickson: "Irisin and FNDC5 in retrospect: An exercise hormone or a transmembrane receptor?" dans: Adipocyte, Vol. 2, Issue 4, pp. 289-93, (2013) (PubMed).

Boström, Wu, Jedrychowski, Korde, Ye, Lo, Rasbach, Boström, Choi, Long, Kajimura, Zingaretti, Vind, Tu, Cinti, Højlund, Gygi, Spiegelman: "A PGC1-?-dependent myokine that drives brown-fat-like development of white fat and thermogenesis." dans: Nature, Vol. 481, Issue 7382, pp. 463-8, (2012) (PubMed).

Détail du antigène

Antigène: FNDC5 (Fibronectin Type III Domain Containing 5 (FNDC5))

Autre désignation: FNDC5 (FNDC5 Produits)

Synonymes: FRCP2 Protein, irisin Protein, 1500001L03Rik Protein, AI836596 Protein, C87088 Protein, PeP Protein, Pxp Protein, fndc5 Protein, si:dkey-264p5.1 Protein, zgc:158684 Protein, fibronectin type III domain containing 5 Protein, fibronectin type III domain containing 5b Protein, FNDC5 Protein, Fndc5 Protein, fndc5b Protein

Sujet: Full Gene Name: fibronectin type III domain containing 5
Synonyms: FRCP2

ID gène: 252995

NCBI Accession: NM_153756

Pathways: Hormone Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation