GATA3 Protein (AA 1-444) (GST tag)

N° du produit ABIN1354834

Détail du produit

Antigène: GATA3 (GATA Binding Protein 3 (GATA3))

Type de proteíne: Recombinant

Attributs du protein: AA 1-444

Origine: Humain

Source: Wheat germ

Purification/Conjugué: Cette GATA3 protéine est marqué à la GST tag.

Application: Western Blotting (WB), ELISA, Antibody Array (AA), Affinity Purification (AP)

Fonction: GATA3 (Human) Recombinant Protein (P02)

Séquence: MEVTADQPRW VSHHHPAVLN GQHPDTHHPG LSHSYMDAAQ YPLPEEVDVL FNIDGQGNHV PPYYGNSVRA TVQRYPPTHH GSQVCRPPLL HGSLPWLDGG KALGSHHTAS PWNLSPFSKT SIHHGSPGPL SVYPPASSSS LSGGHASPHL FTFPPTPPKD VSPDPSLSTP GSAGSARQDE KECLKYQVPL PDSMKLESSH SRGSMTALGG ASSSTHHPIT TYPPYVPEYS SGLFPPSSLL GGSPTGFGCK SRPKARSSTE GRECVNCGAT STPLWRRDGT GHYLCNACGL YHKMNGQNRP LIKPKRRLSA ARRAGTSCAN CQTTTTTLWR RNANGDPVCN ACGLYYKLHN INRPLTMKKE GIQTRNRKMS SKSKKCKKVH DSLEDFPKNS SFNPAALSRH MSSLSHISPF SHSSHMLTTP TPMHPPSSLS FGPHHPSSMV TAMG

Attributs du produit: Human GATA3 full-length ORF ( NP_001002295.1, 1 a.a. - 444 a.a.) recombinant protein with GST-tag at N-terminal.

Purification: in vitro wheat germ expression system

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Preparation method: in vitro, wheat germ expression system
Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

Restrictions: For Research Use only

Stockage

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -80 °C

Stockage commentaire: Best use within three months from the date of receipt of this protein.

Référence

Economou, Datta, Georgiadis, Cadot, Frenz, Maconochie: "Gata3 directly regulates early inner ear expression of Fgf10." dans: Developmental biology, Vol. 374, Issue 1, pp. 210-22, (2013) (PubMed).

Hosokawa, Tanaka, Suzuki, Iwamura, Ohkubo, Endoh, Kato, Endo, Onodera, Tumes, Kanai, Sugano, Nakayama: "Functionally distinct Gata3/Chd4 complexes coordinately establish T helper 2 (Th2) cell identity." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 12, pp. 4691-6, (2013) (PubMed).

Hosokawa, Tanaka, Kato, Shinoda, Tohyama, Hanazawa, Tamaki, Hirahara, Yagi, Sakikawa, Morita, Nagira, Poyurovsky, Suzuki, Motohashi, Nakayama: "Gata3/Ruvbl2 complex regulates T helper 2 cell proliferation via repression of Cdkn2c expression." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 46, pp. 18626-31, (2013) (PubMed).

Kuwahara, Yamashita, Shinoda, Tofukuji, Onodera, Shinnakasu, Motohashi, Hosokawa, Tumes, Iwamura, Lefebvre, Nakayama: "The transcription factor Sox4 is a downstream target of signaling by the cytokine TGF-? and suppresses T(H)2 differentiation." dans: Nature immunology, Vol. 13, Issue 8, pp. 778-86, (2012) (PubMed).

Détail du antigène

Antigène: GATA3 (GATA Binding Protein 3 (GATA3))

Autre désignation: GATA3 (GATA3 Produits)

Synonymes: HDR Protein, HDRS Protein, Gata-3 Protein, jal Protein, cb550 Protein, gta3 Protein, GATA-3 Protein, XGATA3 Protein, xgata-3 Protein, hdr Protein, xGATA-3 Protein, GATA3 Protein, GATA transcription factor 3 Protein, T4L20.260 Protein, T4L20_260 Protein, gata3 Protein, ZH-DR Protein, zgc:103531 Protein, GATA binding protein 3 Protein, GATA binding protein 3 S homeolog Protein, GATA transcription factor 3 Protein, amidase Protein, putative amidase Protein, GATA-binding protein 3 Protein, hematopoietic death receptor Protein, GATA3 Protein, Gata3 Protein, gata3 Protein, gata3.S Protein, gatA3 Protein, hdr Protein

Sujet: Full Gene Name: GATA binding protein 3
Synonyms: HDR,MGC2346,MGC5199,MGC5445

ID gène: 2625

NCBI Accession: NM_001002295

Pathways: Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation