SOD2 Protein (partial) (His tag)

N° du produit ABIN1686709

Détail du produit

Antigène: SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))

Type de proteíne: Recombinant

Attributs du protein: partial

Origine: Rat

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette SOD2 protéine est marqué à la His tag.

Application: Western Blotting (WB), SDS-PAGE (SDS)

Specificité: ~25 kDa

Purification: Affinity Purified

Pureté: >90%

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

This product has been certified >90% pure using SDS-PAGE analysis.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: 50 mM Tris/HCl pH 7.7, 0.3M NaCl

Stock: -20 °C

Détail du antigène

Antigène: SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))

Autre désignation: Mn SOD (SOD2 Produits)

Synonymes: LOC100101896 Protein, MNSOD Protein, GB14346 Protein, sod2 Protein, MGC88869 Protein, Sod2 Protein, CG8905 Protein, Dmel\\CG8905 Protein, Mito SOD Protein, Mn SOD Protein, Mn-SOD Protein, Mn-SOD2 Protein, MnSOD Protein, MnSODII Protein, Mn[2+]SOD Protein, SOD Protein, SOD-2 Protein, SOD2 Protein, Sod-2 Protein, dSOD2 Protein, mitSOD2 Protein, mnSOD Protein, IPOB Protein, MVCD6 Protein, cb463 Protein, wu:fj33b01 Protein, zgc:73051 Protein, MnSOD Protein, manganese superoxide dismutase Protein, superoxide dismutase 2, mitochondrial Protein, superoxide dismutase 2 Protein, Mn superoxide dismutase Protein, Superoxide dismutase 2 (Mn) Protein, superoxide dismutase 2 L homeolog Protein, BDBG_07234 Protein, LOC100101896 Protein, MNSOD Protein, Sod2 Protein, sod2 Protein, LbMnSOD4 Protein, SOD2 Protein, LOC100282741 Protein, SOD-2 Protein, sod2.L Protein

Sujet: Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body (3). It works by catalyzing the dismutation of the superoxide radical O2ˉ to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase (2, 5). In general, SODs play a major role in antioxidant defense mechanisms (4). There are two main types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two cysteines forming an intra-subunit disulphide bridge (3). The second form (SOD2) is a manganese containing enzyme and resides in the mitochondrial matrix. It is a homotetramer of 80 kDa. The third form (SOD3 or EC-SOD) is like SOD1 in that it contains Cu and Zn ions, however it is distinct in that it is a homotetramer, with a mass of 30 kDA and it exists only in the extracellular space(8). SOD3 can also be distinguished by its heparin-binding capacity (1).

Poids moléculaire: approx. 25 kDa

ID gène: 24787

UniProt: P07895

Pathways: Sensory Perception of Sound, Transition Metal Ion Homeostasis, Negative Regulation of intrinsic apoptotic Signaling