SEMA3A Protein (AA 21-771) (His tag)

N° du produit ABIN1691738

Détail du produit

Antigène: SEMA3A (Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A (SEMA3A))

Type de proteíne: Recombinant

Attributs du protein: AA 21-771

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette SEMA3A protéine est marqué à la His tag.

Fonction: Recombinant Human Semaphorin-3A/SEMA3A (C-6His)

Séquence: NYQNGKNNVP RLKLSYKEML ESNNVITFNG LANSSSYHTF LLDEERSRLY VGAKDHIFSF DLVNIKDFQK IVWPVSYTRR DECKWAGKDI LKECANFIKV LKAYNQTHLY ACGTGAFHPI CTYIEIGHHP EDNIFKLENS HFENGRGKSP YDPKLLTASL LIDGELYSGT AADFMGRDFA IFRTLGHHHP IRTEQHDSRW LNDPKFISAH LISESDNPED DKVYFFFREN AIDGEHSGKA THARIGQICK NDFGGHRSLV NKWTTFLKAR LICSVPGPNG IDTHFDELQD VFLMNFKDPK NPVVYGVFTT SSNIFKGSAV CMYSMSDVRR VFLGPYAHRD GPNYQWVPYQ GRVPYPRPGT CPSKTFGGFD STKDLPDDVI TFARSHPAMY NPVFPMNNRP IVIKTDVNYQ FTQIVVDRVD AEDGQYDVMF IGTDVGTVLK VVSIPKETWY DLEEVLLEEM TVFREPTAIS AMELSTKQQQ LYIGSTAGVA QLPLHRCDIY GKACAECCLA RDPYCAWDGS ACSRYFPTAK RATRAQDIRN GDPLTHCSDL HHDNHHGHSP EERIIYGVEN SSTFLECSPK SQRALVYWQF QRRNEERKEE IRVDDHIIRT DQGLLLRSLQ QKDSGNYLCH AVEHGFIQTL LKVTLEVIDT EHLEELLHKD DDGDGSKTKE MSNSMTPSQK VWYRDFMQLI NHPNLNTMDE FCEQVWKRDR KQRRQRPGHT PGNSNKWKHL QENKKGRNRR THEFERAPRS VHHHHHH

Attributs du produit: Recombinant Human Semaphorin-3A/SEMA3A is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Asn21-Val771) of Human SEMA3A fused with a polyhistidine tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: 4 °C/-20 °C/-80 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 5 months

Détail du antigène

Antigène: SEMA3A (Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A (SEMA3A))

Autre désignation: SEMA3A (SEMA3A Produits)

Synonymes: COLL1 Protein, HH16 Protein, Hsema-I Protein, Hsema-III Protein, SEMA1 Protein, SEMAD Protein, SEMAIII Protein, SEMAL Protein, SemD Protein, coll-1 Protein, Semad Protein, COLL-1 Protein, SEMA3A Protein, Dsema3a Protein, Sema3A Protein, sema1a Protein, sema3a1 Protein, semaZ1a Protein, sema1b Protein, sema3a2 Protein, semaZ1b Protein, semaphorin 3A Protein, sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A Protein, Sema-3a Protein, sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa Protein, sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab Protein, SEMA3A Protein, Sema3a Protein, Sema-3a Protein, sema3aa Protein, sema3ab Protein

Sub Type: Fusionprotein

Sujet: Semaphorin-3A is a secreted protein which belongs to the semaphorin family. Semaphorins are a family of secreted and cell-bound signaling molecules defined by the presence of a common 500 aa Sema domain. This protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines.
Alternative Names: Synonyms: Semaphorin III, SEMA3A, SEMAD, Hsema-I, SEMA1, SemD, Semad, coll-1 , Hsema-III, Sema III

Poids moléculaire: 87.3 kDa

UniProt: Q14563

Pathways: Regulation of Cell Size