GCDH Protein (AA 45-438) (His tag)

N° du produit ABIN1692345

Détail du produit

Antigène: GCDH (Glutaryl-CoA Dehydrogenase (GCDH))

Type de proteíne: Recombinant

Attributs du protein: AA 45-438

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette GCDH protéine est marqué à la His tag.

Fonction: Recombinant Human Glutaryl-CoA Dehydrogenase Mitochondrial/GCDH (N-6His)

Séquence: MNHKVHHHHH HMRPEFDWQD PLVLEEQLTT DEILIRDTFR TYCQERLMPR ILLANRNEVF HREIISEMGE LGVLGPTIKG YGCAGVSSVA YGLLARELER VDSGYRSAMS VQSSLVMHPI YAYGSEEQRQ KYLPQLAKGE LLGCFGLTEP NSGSDPSSME TRAHYNSSNK SYTLNGTKTW ITNSPMADLF VVWARCEDGC IRGFLLEKGM RGLSAPRIQG KFSLRASATG MIIMDGVEVP EENVLPGASS LGGPFGCLNN ARYGIAWGVL GASEFCLHTA RQYALDRMQF GVPLARNQLI QKKLADMLTE ITLGLHACLQ LGRLKDQDKA APEMVSLLKR NNCGKALDIA RQARDMLGGN GISDEYHVIR HAMNLEAVNT YEGTHDIHAL ILGRAITGIQ AFTASK

Attributs du produit: Recombinant Human Glutaryl-CoA Dehydrogenase Mitochondrial/GCDH is produced with our E. coli expression system. The target protein is expressed with sequence (Arg45-Lys438) of Human GCDH fused with a His tag at the N-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM HEPES, 150 mM NaCl, pH 7.4.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: -80 °C

Stockage commentaire: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Date de péremption: 6 months

Détail du antigène

Antigène: GCDH (Glutaryl-CoA Dehydrogenase (GCDH))

Autre désignation: GCDH (GCDH Produits)

Synonymes: ACAD5 Protein, GCD Protein, zgc:56505 Protein, zgc:77704 Protein, 9030411L18 Protein, AI266902 Protein, D17825 Protein, glutaryl-CoA dehydrogenase Protein, glutaryl-CoA dehydrogenase a Protein, glutaryl-Coenzyme A dehydrogenase Protein, GCDH Protein, Gcdh Protein, gcdha Protein

Sub Type: Fusionprotein

Sujet: Glutaryl-CoA Dehydrogenase Mitochondrial (GCDH) is an enzyme that acts upon glutaryl-coenzyme A, creating crotonyl-coenzyme A. It plays a role in the metabolism of lysine, hydroxylysine and tryptophan. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive Glutaryl-CoA and electron-transfer flavoprotein to (E)-but-2-enoyl-CoA, CO2 and reduced electron-transfer flavoprotein. A defect in this enzyme is associated with neurological condition glutaric acidemia type 1 and cause a progressive form of early-onset generalized dystonia.
Alternative Names: Glutaryl-CoA Dehydrogenase Mitochondrial, GCD, GCDH

Poids moléculaire: 45 kDa

UniProt: Q92947