HLA-E Protein (AA 1-358) (GST tag)

N° du produit ABIN1989653

Détail du produit

Antigène: HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))

Type de proteíne: Recombinant

Attributs du protein: AA 1-358

Origine: Humain

Source: Wheat germ

Purification/Conjugué: Cette HLA-E protéine est marqué à la GST tag.

Application: Western Blotting (WB), ELISA, Affinity Purification (AP), Antibody Array (AA)

Fonction: HLA-E (Human) Recombinant Protein (P01)

Séquence: MVDGTLLLLL SEALALTQTW AGSHSLKYFH TSVSRPGRGE PRFISVGYVD DTQFVRFDND AASPRMVPRA PWMEQEGSEY WDRETRSARD TAQIFRVNLR TLRGYYNQSE AGSHTLQWMH GCELGPDRRF LRGYEQFAYD GKDYLTLNED LRSWTAVDTA AQISEQKSND ASEAEHQRAY LEDTCVEWLH KYLEKGKETL LHLEPPKTHV THHPISDHEA TLRCWALGFY PAEITLTWQQ DGEGHTQDTE LVETRPAGDG TFQKWAAVVV PSGEEQRYTC HVQHEGLPEP VTLRWKQASQ PTIPIVGIIA GLVLLGSVVS GAVVAAVIWR KKSSGGKGGS YSKAEWSDSA QGSESHSL

Attributs du produit: Human HLA-E full-length ORF (no protein_acc, 1 a.a. - 358 a.a.) recombinant protein with GST tag at N-terminal.

Purification: in vitro wheat germ expression system

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -80 °C

Stockage commentaire: Best use within three months from the date of receipt of this protein.

Détail du antigène

Antigène: HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))

Autre désignation: HLA-E (HLA-E Produits)

Synonymes: EA1.2 Protein, EA2.1 Protein, HLA-6.2 Protein, MHC Protein, QA1 Protein, major histocompatibility complex, class I, E Protein, HLA-E Protein, PATR-E Protein

Sujet: Synonyms: DKFZp686P19218,EA1.2,EA2.1,HLA-6.2,MHC,QA1
Gene Description: major histocompatibility complex, class I, E
Gene Name: HLA-E
Gene Summary: HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.
GenBank: AK098434.1

Poids moléculaire: 66.6 kDa (theoreatical)

ID gène: 3133

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process