NR4A3 Protein (AA 1-626) (GST tag)

N° du produit ABIN1989820

Détail du produit

Antigène: NR4A3 (Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3))

Type de proteíne: Recombinant

Attributs du protein: AA 1-626

Origine: Humain

Source: Wheat germ

Purification/Conjugué: Cette NR4A3 protéine est marqué à la GST tag.

Application: Western Blotting (WB), ELISA, Affinity Purification (AP), Antibody Array (AA)

Fonction: NR4A3 (Human) Recombinant Protein (P01)

Séquence: MPCVQAQYSP SPPGSSYAAQ TYSSEYTTEI MNPDYTKLTM DLGSTEITAT ATTSLPSIST FVEGYSSNYE LKPSCVYQMQ RPLIKVEEGR APSYHHHHHH HHHHHHHHQQ QHQQPSIPPA SSPEDEVLPS TSMYFKQSPP STPTTPAFPP QAGALWDEAL PSAPGCIAPG PLLDPPMKAV PTVAGARFPL FHFKPSPPHP PAPSPAGGHH LGYDPTAAAA LSLPLGAAAA AGSQAAALES HPYGLPLAKR AAPLAFPPLG LTPSPTASSL LGESPSLPSP PSRSSSSGEG TCAVCGDNAA CQHYGVRTCE GCKGFFKRTV QKNAKYVCLA NKNCPVDKRR RNRCQYCRFQ KCLSVGMVKE VVRTDSLKGR RGRLPSKPKS PLQQEPSQPS PPSPPICMMN ALVRALTDST PRDLDYSRYC PTDQAAAGTD AEHVQQFYNL LTASIDVSRS WAEKIPGFTD LPKEDQTLLI ESAFLELFVL RLSIRSNTAE DKFVFCNGLV LHRLQCLRGF GEWLDSIKDF SLNLQSLNLD IQALACLSAL SMITERHGLK EPKRVEELCN KITSSLKDHQ SKGQALEPTE SKVLGALVEL RKICTLGLQR IFYLKLEDLV SPPSIIDKLF LDTLPF

Attributs du produit: Human NR4A3 full-length ORF (NP_008912.2, 1 a.a. - 626 a.a.) recombinant protein with GST tag at N-terminal.

Purification: in vitro wheat germ expression system

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -80 °C

Stockage commentaire: Best use within three months from the date of receipt of this protein.

Détail du antigène

Antigène: NR4A3 (Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3))

Autre désignation: NR4A3 (NR4A3 Produits)

Synonymes: CHN Protein, CSMF Protein, MINOR Protein, NOR1 Protein, TEC Protein, AI573420 Protein, NOR-1 Protein, Nor1 Protein, NOR-2 Protein, NR4A3 Protein, Nr4a3 Protein, nuclear receptor subfamily 4 group A member 3 Protein, nuclear receptor subfamily 4, group A, member 3 Protein, NR4A3 Protein, Nr4a3 Protein, nr4a3 Protein

Sujet: Synonyms: CHN,CSMF,MINOR,NOR1,TEC
Gene Description: nuclear receptor subfamily 4, group A, member 3
Gene Name: NR4A3
Gene Summary: This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcriptional activator. The protein can efficiently bind the NGFI-B Response Element (NBRE). Three different versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene and other genes. The translocation breakpoints are associated with Nuclear Receptor Subfamily 4, Group A, Member 3 (on chromosome 9) and either Ewing Sarcome Breakpoint Region 1 (on chromosome 22), RNA Polymerase II, TATA Box-Binding Protein-Associated Factor, 68-KD (on chromosome 17), or Transcription factor 12 (on chromosome 15). Four transcript variants encoding three distinct isoforms have been identified for this gene.

Poids moléculaire: 94.6 kDa (theoreatical)

ID gène: 8013

NCBI Accession: NM_006981

Pathways: Fc-epsilon Receptor Signaling Pathway, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway