CCL6 Protéine

N° du produit ABIN2017706

Détail du produit

Antigène: CCL6 (Chemokine (C-C Motif) Ligand 6 (CCL6))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Souris

Source: Escherichia coli (E. coli)

Séquence: GLIQEIEKED RRYNPPIIHQ GFQDTSSDCC FSYATQIPCK RFIYYFPTSG GCIKPGIIFI SRRGTQVCAD PSDRRVQRCL STLKQGPRSG NKVIA

Attributs du produit: Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human CCR1 transfected murine BaF3 cells is in a concentration range of 10-100 ng/mL.

Pureté: > 97 % by SDS-PAGE and HPLC analyses.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 1 EU/μg of rMuC10/CCL6 as determined by LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.

Buffer: Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM Tris, pH 8.0, 500 mM NaCl.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C.

Détail du antigène

Antigène: CCL6 (Chemokine (C-C Motif) Ligand 6 (CCL6))

Autre désignation: C10/CCL6 (CCL6 Produits)

Synonymes: MRP-1 Protein, Scya6 Protein, c10 Protein, Abcc1a Protein, Avcc1a Protein, Mrp Protein, Mrp1 Protein, Mrp-1 Protein, Scay6 Protein, chemokine (C-C motif) ligand 6 Protein, ATP binding cassette subfamily C member 1 Protein, Ccl6 Protein, Abcc1 Protein

Sujet: Chemokine (C-C motif) ligand 6 (CCL6) is a small cytokine belonging to the CC chemokine family that has only been identified in rodents. Murine C10 is expressed in myelopoietic bone marrow cultures when stimulated with GM-CSF, M-CSF, IL-3 or IL-4. It signals primarily through the CCR1 receptor. C10 is chemotactic for B cells, CD4+ T cells, monocytes and NK cells and also exhibits powerful suppressive activity on colony formation by different lineages of hematopoietic progenitors. The C10 contains the four highly conserved cysteine residues present in CC chemokines.
Synonyms: CCL6, MRP-1

Poids moléculaire: 10.7 kDa, a single non-glycosylated polypeptide chain containing 95 amino acids.