IL-3 Protein (AA 20-152)
Aperçu rapide pour IL-3 Protein (AA 20-152) (ABIN2018017)
Antigène
Voir toutes IL-3 ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Attributs du protein
- AA 20-152
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Attributs du produit
- ED50 < 0.1 ng/mL, measured in a cell proliferation assay using TF-1 cells, corresponding to a specific activity of > 1x10^7 units/mg.
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niveau d'endotoxine
- < 0.2 EU/μg, determined by LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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Buffer
- Lyophilized after extensive dialysis against PBS.
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Stock
- -80 °C
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Stockage commentaire
- Lyophilized recombinant human Interlerkin 3 (IL-3) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhIL-3 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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Date de péremption
- 6 months
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- IL-3 (Interleukin 3 (IL-3))
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Sujet
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Interleukin-3 (IL-3) is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine.Recombinant human interleukin 3 expressed in CHO cells is glycosylated protein with molecular weight range from 17 to 30 kDa shown in non-reducing SDS-PAGE.
Synonyms: MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor -
Poids moléculaire
- 17-30 kDa, observed by non-reducing SDS-PAGE.
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UniProt
- Q6GS87
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Pathways
- Signalistation JAK/STAT, Regulation of Carbohydrate Metabolic Process, Autophagy
Antigène
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