FGF7 Protein (AA 32-194)
Aperçu rapide pour FGF7 Protein (AA 32-194) (ABIN2018177)
Antigène
Voir toutes FGF7 ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Attributs du protein
- AA 32-194
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Attributs du produit
- ED50 < 1 ng /mL, measured in a proliferation assay using 4MBr5 cells.
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niveau d'endotoxine
- < 0.2 EU/μg, determined by LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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Buffer
- Lyophilized after extensive dialysis against PBS.
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Stock
- -80 °C
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Stockage commentaire
- Lyophilized recombinant human Keratinocyte Growth Factor(rhKGF) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Keratinocyte Growth Factor should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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Date de péremption
- 6 months
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- FGF7 (Fibroblast Growth Factor 7 (FGF7))
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Autre désignation
- Keratinocyte Growth Factor (KGF)
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Sujet
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Keratinocyte Growth Factor (KGF), also known as FGF-7 and HBGF-7, is a mitogen factor belonging to the heparin-binding growth factor family. It is expressed mainly by epithelial cells. KGF binds to fibroblast growth factor receptor 2b (FGFR2b) to form a dimeric complex and initiate downstream signals. KGF plays an important role in embryonic development, cell proliferation and differentiation. It has also been reported to function in kidney and lung development, angiogenesis, wound healing and tumor invasion.
Synonyms: Keratinocyte Growth Factor, Fibroblast Growth Factor-7, HBGF-7 -
Poids moléculaire
- 16-18 kDa, observed by reducing SDS-PAGE.
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UniProt
- P21781
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Pathways
- Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Antigène
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