CCL7 Protéine
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- Antigène Voir toutes CCL7 Protéines
- CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
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Origine
- Rat
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Source
- Escherichia coli (E. coli)
- Séquence
- QPDGTNSSTC CYVKKQKIPK RNLKSYRKIT SSRCPWEAVI FKTKKGMEVC AEAHQKWVEE AIAYLDMKTS TPKP
- Attributs du produit
- Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human monocytes is in a concentration range of 10-100 ng/mL.
- Pureté
- > 95 % by SDS-PAGE and HPLC analyses.
- Stérilité
- 0.2 μm filtered
- niveau d'endotoxine
- < 1 EU/μg of rRtMCP-3/CCL7 as determined by LAL method.
- Top Product
- Discover our top product CCL7 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
- Buffer
- Lyophilized from a 0.2 μm filtered concentrated solution in 2 x PBS, pH 7.4.
- Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C.
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- Antigène
- CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))
- Autre désignation
- MCP-3/CCL7 (CCL7 Produits)
- Synonymes
- CCL7 Protein, FIC Protein, MARC Protein, MCP-3 Protein, MCP3 Protein, NC28 Protein, SCYA6 Protein, SCYA7 Protein, Scya7 Protein, fic Protein, marc Protein, mcp3 Protein, C-C motif chemokine ligand 7 Protein, chemokine (C-C motif) ligand 7 Protein, CCL7 Protein, Ccl7 Protein
- Sujet
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Monocyte Chemotactic Protein-3 (MCP3) and CCL7 are two monocyte chemotactic proteins produced by human MG63 osteosarcoma cells. Both MCP3 and CCL7 are members of the CC family of chemokines and share 62 % and 71 % amino acid sequence identity, respectively, with MCP1. CCL7 also shares 58 % amino acid identity with MCP3.Similarly to other CC chemokines, all three MCP proteins are monocyte chemoattractants. In addition, the three MCPs can chemoattract activated NK cells as well as CD4+ and CD8+ T lymphocytes. All three cytokines have also been shown to attract eosinophils and induce histamine secretion from basophils.
Synonyms: C-C motif chemokine 7, Monocyte chemoattractant protein 3, Monocyte chemotactic protein 3, MCP-3, Small-inducible cytokine A7, Ccl7, Mcp3, Scya7. - Poids moléculaire
- 8.5 kDa, a single non-glycosylated polypeptide chain containing 74 amino acids.
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