CCL23 Protein (AA 32-494, AA 495-728)

N° du produit ABIN2018263

Détail du produit

Antigène: CCL23 (Chemokine (C-C Motif) Ligand 23 (CCL23))

Type de proteíne: Recombinant

Activité biologique: Active

Attributs du protein: AA 32-494, AA 495-728

Origine: Humain

Source: CHO Cells

Attributs du produit: The EC50 value of human MPIF-1/CCL23 on Ca2+ mobilization assay in CHO-K1/Ga15/hCCR1 cells (human Ga15 and human CCR1 stably expressed in CHO-K1 cells) is less than 2 μg/mL.
Alpha chain: AA 32-494, beta chain: AA 495-728

Pureté: > 98 % as analyzed by SDS-PAGE.

niveau d'endotoxine: < 0.2 EU/μg, determined by LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstituted in ddH2O or PBS at 100 μg/mL.

Buffer: Lyophilized after extensive dialysis against PBS.

Stock: -80 °C

Stockage commentaire: Lyophilized recombinant humanMPIF-1/CCL23 remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human MPIF-1/CCL23 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

Date de péremption: 6 months

Détail du antigène

Antigène: CCL23 (Chemokine (C-C Motif) Ligand 23 (CCL23))

Autre désignation: MPIF-1/CCL23 (CCL23 Produits)

Synonymes: CK-BETA-8 Protein, CKb8 Protein, Ckb-8 Protein, Ckb-8-1 Protein, MIP-3 Protein, MIP3 Protein, MPIF-1 Protein, SCYA23 Protein, hmrp-2a Protein, C-C motif chemokine 23 Protein, C-C motif chemokine ligand 23 Protein, chemokine (C-C motif) ligand 23 Protein, LOC508666 Protein, CCL23 Protein

Sujet: Myeloid progenitor inhibitory factor 1 (MPIF-1), also known as Chemokine (C-C motif) ligand 23 (CCL23) is a small cytokine belonging to the CC chemokine family.MPIF-1is predominantly expressed in lung and liver tissue, but is also found in bone marrow and placenta. It is also expressed in some cell lines of myeloid origin. It is highly chemotactic for resting T cells and monocytes and slightly chemotactic for neutrophils. MPIF-1 has been shown to inhibit colony formation of bone marrow myeloid immature progenitors. It has also been attributed to an inhibitory activity on hematopoietic progenitor cells. MPIF-1 is a ligand for the chemokine receptor CCR1.Recombinant human MPIF-1/CCL23 produced in CHO cells is a single polypeptide chain containing 99 amino acids. A fully biologically active molecule, rhMPIF-1/CCL23 has a molecular mass of 12 kDa analyzed by reducing SDS-PAGE.
Synonyms: MPIF-1/CCL23, Human

Poids moléculaire: 12 kDa, observed by reducing SDS-PAGE.