NOV Protein (AA 32-357)
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- Antigène Voir toutes NOV Protéines
- NOV (Nephroblastoma Overexpressed (NOV))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 32-357
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Origine
- Humain
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Source
- CHO Cells
- Attributs du produit
- ED50 < 5 μg/mL, measured in a cell proliferation assay using 3T3 cells.
- Pureté
- > 95 % as analyzed by SDS-PAGE and HPLC.
- niveau d'endotoxine
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product NOV Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Stock
- -80 °C
- Stockage commentaire
- Lyophilized recombinant Human NOV remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human NOV should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- Date de péremption
- 6 months
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- Antigène
- NOV (Nephroblastoma Overexpressed (NOV))
- Autre désignation
- Nephroblastoma Overexpressed Gene Protein (NOV) (NOV Produits)
- Synonymes
- CCN3 Protein, IBP-9 Protein, IGFBP-9 Protein, IGFBP9 Protein, NOVh Protein, nov-A Protein, xnov Protein, NovH Protein, C130088N23Rik Protein, nephroblastoma overexpressed Protein, nephroblastoma overexpressed L homeolog Protein, nephroblastoma overexpressed gene Protein, NOV Protein, nov.L Protein, Nov Protein
- Sujet
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Nephroblastoma Overexpressed Gene Protein (NOV), also known as CCN3, IGFBP9 and NOVH, is one of the CCN family of secreted proteins. It is expressed in bone marrow, thymic cells and nephroblastoma. NOV signals through integrin receptors, NOTCH1 and fibulin 1c to regulate multiple cellular activities, such as cell adhesion, migration, proliferation and differentiation. The reported functions of NOV are diverse. It has been reported to play a role in angiogenesis and stem cell self-renewal. It has also been implicated in osteogenic differentiation, embryo development and cancer pathogenesis.
Synonyms: Nephroblastoma Overexpressed gene, CCN3, IGFBP9, NovH - Poids moléculaire
- 20-50 kDa, observed by reducing SDS-PAGE.
- UniProt
- P48745
- Pathways
- Smooth Muscle Cell Migration, Growth Factor Binding
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