FTL Protein (AA 1-175) (His tag)

N° du produit ABIN2115453

Détail du produit

Antigène: FTL (Ferritin, Light Polypeptide (FTL))

Type de proteíne: Recombinant

Attributs du protein: AA 1-175

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette FTL protéine est marqué à la His tag.

Fonction: Recombinant Human Ferritin Light Chain/FTL (N-6His)

Séquence: MNHKVHHHHH HMSSQIRQNY STDVEAAVNS LVNLYLQASY TYLSLGFYFD RDDVALEGVS HFFRELAEEK REGYERLLKM QNQRGGRALF QDIKKPAEDE WGKTPDAMKA AMALEKKLNQ ALLDLHALGS ARTDPHLCDF LETHFLDEEV KLIKKMGDHL TNLHRLGGPE AGLGEYLFER LTLKHD

Attributs du produit: Recombinant Human FTL is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Asp175) of Human FTL fused with a polyhistidine tag at the N-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.5.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: 4 °C/-20 °C/-80 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: FTL (Ferritin, Light Polypeptide (FTL))

Autre désignation: Ferritin Light Chain (FTL Produits)

Synonymes: NBIA3 Protein, apoferritin Protein, ferritin Protein, fhc Protein, fth Protein, fth1 Protein, fthl6 Protein, ftn-2 Protein, pig15 Protein, plif Protein, FT Protein, Ftl Protein, Ftl-1 Protein, L-ferritin Protein, FTL Protein, Ftl1 Protein, FTL2 Protein, FTD Protein, ferritin light chain Protein, ferritin, heavy polypeptide 1 L homeolog Protein, ferritin light polypeptide 1 Protein, ferritin, light polypeptide Protein, ferritin light-chain Protein, ferritin light chain 1 Protein, FTL Protein, fth1.L Protein, Ftl1 Protein, CpipJ_CPIJ004069 Protein, Ftl Protein

Sujet: Ferritin is a large, iron-storage heteropolymeric protein,which is expressed in most kinds of cells and co-assemble in different proportion in a tissue-specific manner. Ferritin has oligomer of 24 subunits and two types of subunits including light chain(FTL) and heavy chain. Ferritin can remove Fe (II) from solution in the presence of oxygen and is very important for iron homeostasis. Iron is absorbed in the ferrous form and deposited as ferric hydroxides after oxidation. Iron is first oxidized to the ferric state for storage as ferric oxyhdroxide whithin the protein shell of ferritin. Thus, ferritin removes excess iron from the cell sap where it could otherwise participate in peroxidation mechanisms. Ferritin also plays a role in delivery of iron to cells and mediates iron uptake in capsule cells of the developing kidney.
Synonyms: Ferritin L subunit,Ferritin light chain, FTL

Poids moléculaire: 24.5 kDa

UniProt: P02792

Pathways: Transition Metal Ion Homeostasis