GLP-1 Protéine

N° du produit ABIN2468485

Détail du produit

Antigène: GLP-1 (Glucagon-like peptide 1 (GLP-1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Séquence: HAEGTFTSDV SSYLEGQAAK EFIAWLVKGR G

Pureté: < 98 % by SDS-PAGE gel and HPLC analyses.

niveau d'endotoxine: Endotoxin level is less than 0.1 ng per μg (1 EU/μg).

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Conseil sur la manipulation: As with any protein, exposing GLP-1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Stock: -20 °C

Stockage commentaire: The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted GLP-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.

Date de péremption: 24 months

Détail du antigène

Antigène: GLP-1 (Glucagon-like peptide 1 (GLP-1))

Autre désignation: GLP-1 (GLP-1 Produits)

Synonymes: GLP1 Protein, GLP2 Protein, GRPP Protein, GLP-1 Protein, Glu Protein, PPG Protein, glucagon Protein, GCG Protein, Gcg Protein

Sujet: GLP-1 is a proglucagon-derived peptide hormone secreted primarily by intestinal L cells during feeding. Its major physiological function is stimulation of pancreatic beta-cells to release appropriate amounts of insulin after glucose absorption. Other biological actions exhibited by GLP-1 include suppression of plasma glucagons levels, inhibition of gastric motility, and promotion of satiety. The secretion of GLP-1 from intestinal L cells is stimulated by nutrients, hormones, and neural inputs. On the other hand, insulin has been reported to inhibit GLP-1 release, indicating that a feedback loop mechanism regulates GLP-1 secretion. In addition to being the precursor of GLP-1, proglucagon, whose primary structure is highly conserved in mammalian species, is also the precursor for other members of the glucagon family of peptide hormones including glicentin-related pancreatic peptide (GRPP), glucagons, and GLP-2. Recombinant human GLP-1 is a 3.3 kDa consisting of 31 amino acid residues.

ID gène: 2641

NCBI Accession: NP_002045

OMIM: 4503945

UniProt: P01275