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LRRC4 Protein (His tag)

LRRC4 Origine: Humain Hôte: HEK-293 Cells Recombinant >92 % as determined by SDS-PAGE. ELISA, WB Active
N° du produit ABIN2566807
  • Antigène Voir toutes LRRC4 Protéines
    LRRC4 (Leucine Rich Repeat Containing 4 (LRRC4))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Origine
    • 5
    • 3
    • 1
    Humain
    Source
    • 4
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette LRRC4 protéine est marqué à la His tag.
    Application
    ELISA, Western Blotting (WB)
    Attributs du produit

    Measured by its binding ability in a functional ELISA. Immobilized Recombinant mouse Netrin-G2a Fc chimera at 4 μg/mL, can bind rhLRRC4 with an apparent KD < 10 nM.

    Pureté
    >92 % as determined by SDS-PAGE.
    Top Product
    Discover our top product LRRC4 Protéine
  • Indications d'application
    This recombinant protein can be used for WB, ELISA. For research use only.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Stock
    -80 °C,-20 °C
    Stockage commentaire
    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
  • Antigène
    LRRC4 (Leucine Rich Repeat Containing 4 (LRRC4))
    Autre désignation
    NGL 2 (LRRC4 Produits)
    Synonymes
    NGL-2 Protein, MBAG1 Protein, NLG-2 Protein, Nag14 Protein, leucine rich repeat containing 4 Protein, LRRC4 Protein, Lrrc4 Protein
    Sujet
    LRRC4 (Leu-rich repeat/LRR-containing glycoprotein 4), LRRC4B and LRRC4C are post-synaptic adhesion molecules of the LRR protein family that induce excitatory synapse formation. LRRC4 is also known as Brain tumor-associated protein BAG, Netrin-G2 ligand (NGL-2), Nasopharyngeal carcinoma-associated gene 14 protein (NAG14), which contains 1 Ig-like (immunoglobulin-like) domain and 9 LRR (leucine-rich) repeats, 1 LRRCT domain, 1 LRRNT domain. LRRC4 / NGL-2 specifically expressed in brain. LRRC4 / NGL-2 regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. LRRC4 / NGL-2 organize the lamina/pathway-specific differentiation of dendrites. LRRC4 / NGL-2 plays a important role for auditory synaptic responses and involved in the suppression of glioma.
    Poids moléculaire
    55.6 kDa
    ID gène
    64101
    UniProt
    Q9HBW1
    Pathways
    Synaptic Membrane
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